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Objective The aim of this study was to evaluate the viability of stem cells from exfoliated and deciduous teeth (SHED) on dentin surface treated with triple antibiotic paste or calcium hydroxide. Materials and Methods Nine single-rooted extracted premolars were prepared appropriately and divided into three groups. In group A, the root canals were left empty, a triple antibiotic paste was placed in the root canals of group B, and calcium hydroxide was placed in the root canals of group C. After 1 week, the intracanal medicaments were removed, and stem cells were seeded on the treated surface of the specimens for 1 more week. The cells were stained and then observed under confocal microscope over the entire surface of each test material. Counting of the cells was made by Image J (3D) software, as well as manually. Statistical Analysis To investigate any statistically significant differences between the experimental groups, statistical tests including Kruskal–Wallis and Mann–Whitney U-test were performed. Significance level was set to P < 0.05, and all analyses were performed with SPSS IBM program, v. 21. Results Groups B and C showed statistically significantly higher number of cells compared to Group A, whereas cells developed in a substrate of calcium hydroxide residues appeared in majority with distinct cores and widened unlike other groups. Conclusions The effect of calcium hydroxide manifested better results regarding the number of stems cells on root canal surfaces.

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Aim Spin refers to reporting, interpretation and extrapolation‐related distortion or manipulation of the findings of a study. The aim of this report was to identify the prevalence and extent of spin in the abstracts of systematic reviews (SRs) including meta‐analyses in the scientific field of endodontics. Methodology A sensitive and inclusive search strategy in PubMed was developed to identify eligible SRs with meta‐analyses in endodontics, supplemented by an electronic search within 3 major specialty journals, from January 1, 2010, to April 16, 2022. Inclusion and extent of spin were recorded, per domain and following issues related to misleading reporting, interpretation and inappropriate extrapolation of meta‐analyses' findings. Association of spin with publication characteristics such as year, journal type, number of authors, continent of authorship, funding, primary study design and significance of the outcome was explored. Results A total of 186 SRs with meta‐analyses were retrieved, and inclusion of spin was detected in 125 abstracts (67.2%), for one or more domains. Most abstracts were affected by more than one type of spin (91/125; 72.8%). There was evidence that abstracts of meta‐analyses of non‐significant findings had 60% lower odds for inclusion of spin (odds ratio, OR: 0.40; 95% CI: 0.19, 0.83; p = .04), after adjusting for year, journal type and number of authors. Conclusions Misleading reporting and misinterpretation of findings in abstracts of meta‐analyses are evident in endodontic research. Efforts should be reinforced to increase awareness within the scientific and academic community to improve adherence to transparent reporting and interpretation.

In Discussion, paragraph 5, sentence 5 should read: This contrasts with the existing view that the use of Ca(OH) 2 in regenerative endodontics may be questionable because of the potential toxicity to human cells. 29