Injection of Teflon paste is a commonly accepted procedure to improve the caliber of voice in unilateral vocal cord paralysis. There are several drawbacks to Teflon injection, among them respiratory obstruction (from overinjected Teflon) and unsatisfactory voice quality (Teflon causes stiffness of the vocal folds). This paper is a preliminary report on lipoinjection instead of Teflon injection into a paralyzed vocal fold. Fat appears to impart a soft bulkiness to the injected cord, while allowing it to retain its vibratory qualities. It is autologous material and can be retrieved if excessively overinjected. The fate of autologous fat injected into a paralyzed vocal cord remains unknown. Most of the literature on lipoinjection concerns repairs of depressed scars or breast augmentation. Our longest follow-up has been 12 months. Three patients have had this procedure, and the results appear to be very encouraging.

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ΧΙΠ Certain strains of mice have hereditary lesions of the inner ear, some present at birth, others developing postnatally, which offer an opportunity to study the physiological characteristics of degenerative deafness. Gruenberg et al.' have made observations on cochlear potentials of the developing Shaker-1 mouse. Mikaelian and Ruben^ reported the cochlear potentials, VIII nerve action potentials and responses from single units of the VIII nerve during the development and degeneration of hearing in the Shaker-1 mouse. This was correlated with histology and behavioral response. DeoP ° studied the histolog ical appearance of the labyrinth and the behavioral response in Shaker-1, Varitint-waddler and df/df mice.In this study the parameters for the physiological acoustical responses were determined in the normal mice and the results were then compared to those of the deaf mice. METHODThe mice used in the present experiments were of four types, a normal group of CBA-J strain and three deaf groups, Shaker-1, Varitint-waddler and the uncomplicated deafness strain, df/df. The

In disorders of the auditory organ associated with hearing loss, a correlation of the anatomical, behavioral and electrophysiological studies furnishes the investigator several parameters of study to better comprehend the hearing mechanism and the various anatomical structural dysfunctions that relate to the hearing loss. Mice are interesting to study because they carry several types of genes for hereditary deafness. Until recently, it was very difficult to train mice for behavioral hearing threshold testing; however, having developed such a method, the next step was to study the normal mice in these three parameters and extend the studies to mice with hereditary hearing loss. The type of mouse studied in this research was the C57/b16 strain which carries such a gene. The results of the studies indicate that the results of the behavioral and electrophysiological studies relate well to each other, and that light microscopic studies (if taken alone) do not furnish us with the actual functional capability of the structures of the inner ear. It is recommended (and it would be most valuable) that efforts should be made to collect and study human temporal bones with all three parameters of study for a better understanding of the structures of the human inner ear. Reference is made and recommendations given as to the parameters of studies while performing human electrocochleography.