Subjective well-being is one indicator of individual's and society's quality of life. Adolescent subjective well-being should therefore be studied to understand the factors that may promote life satisfaction and positive affect of adolescents. These factors mitigate the negative effects of stressful life events against the development of psychological and behavioral problems.This study aims to determine the role of self-esteem, forgiveness, and perception of family harmony in subjective well-being of adolescents. Subjects of this study were 226 adolescents (aged 12-21 years old). The result of multiple regression analysis indicated that self-esteem, forgiveness, and perception of family harmony simultaneously served as predictors of subjective well-being in adolescents (F=48.271; p<.01). However, from beta coefficients of each predictor, it was evident that only self-esteem served as a predictor of adolescents' subjective well-being (p<.01), whereas forgiveness and perception of family harmony did not serve as predictors of subjective well-being in adolescents (p>.05). The results also showed that the coefficient of multiple determination for subjective well-being was 0.387 (seen from Adjusted R Square), meaning that 38.7% variance of subjective well-being in adolescents of this study was influenced by self-esteem, forgiveness, and the perception of family harmony, while 61.3% was influenced by other variables.