Background/Objectives: Milk intake is widely recommended for a healthy diet. Epidemiological studies have suggested that the consumption of dairy products may be associated with a reduction in type 2 diabetes mellitus (T2DM). A meta-analysis was conducted to elucidate the association between dairy products consumption and T2DM. Subjects/Methods: A systematical literature search was done through the Medline database and seven related cohort studies were identified. The adjusted relative risks (RRs) with the highest and the lowest categories from each study were extracted to calculate the combined RR. A least-square trend estimation was applied to assess the dose-response relationships. Results: A combined RR of 0.86 (95% confidence interval (CI), 0.79-0.92) was revealed on T2DM risk associated to dairy intake, with little evidence of heterogeneity. For subgroup analysis, a combined RR was 0.82 (95% CI, 0.74-0.90), 1.00 (95% CI, 0.89-1.10), 0.95 (95% CI, 0.86-1.05) and 0.83 (95% CI, 0.74-0.93) for the intake of low-fat dairy, high-fat dairy, whole milk and yogurt, respectively. Dose-response analysis showed that T2DM risk could be reduced 5% for total dairy products and 10% for low-fat dairy products. Conclusion: An inverse association of daily intake of dairy products, especially low-fat dairy, with T2DM was revealed, indicating a beneficial effect of dairy consumption in the prevention of T2DM development.
This study examined the association of dietary calcium intake with incident type 2 diabetes by a meta-analysis and explored the potential confounding by magnesium. Potential studies were identified by searching the PubMed database in September 2011. Prospective cohort studies that reported relative risks (RR) with 95% confidence intervals (CI) of type 2 diabetes for dietary calcium intake were selected. Results were combined using either a fixed-or random-effects model. Six prospective cohort studies comprising 264 268 participants and 11 225 reported cases were included. All combined random-effects metaanalysis yielded a significant pooled RR of 0.85 (95% CI 0.75 --0.97). However, a sensitivity analysis limited to four studies with control for magnesium yielded an attenuated, nonsignificant pooled RR of 0.94 (95% CI 0.85 --1.05). In conclusion, dietary calcium intake was not independently associated with risk of type 2 diabetes. The inverse association in prior observational studies may be partially confounded by magnesium intake.
We propose a light-emitting diode headlamp for motorcycles based on freeform micro-lenses. The freeform micro-lenses include a collimator and micro-lens structures. The rays emitted by the light-emitting diode source are first collimated and then redistributed by the microstructures. We make a point by point relationship between the light-emitting diode source and the target plane according to Economic Commission for Europe Regulation R113 revision 2. Simulation results show that the light pattern of our proposed headlamp could satisfy the requirements of the regulation. Illuminance on the test points, lines, and zones can fully meet the Economic Commission for Europe Regulation. The optical efficiency of our proposed headlamp could reach up to 90%, which is much higher than the traditional design.
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