Thiabendazole (TBZ) is a fungicide and anthelmintic drug commonly found in food products. Due to its toxicity and potential carcinogenicity, its determination in various samples is important for public health. Different analytical methods can be used to determine the presence and concentration of TBZ in samples. Liquid chromatography (LC) and its subtypes, high-performance liquid chromatography (HPLC) and ultra-high-performance liquid chromatography (UHPLC), are the most commonly used methods for TBZ determination representing 19%, 18%, and 18% of the described methods, respectively. Surface-enhanced Raman spectroscopy (SERS) and fluorimetry are two more methods widely used for TBZ determination, representing 13% and 12% of the described methods, respectively. In this review, a number of methods for TBZ determination are described, but due to their limitations, there is a high potential for the further improvement and development of each method in order to obtain a simple, precise, and accurate method that can be used for routine analysis.

In previous papers we have shown that the use of the atomic resolution STEM to study adsorption of heavy atoms on light element substrates could be of potential value in surface science. We indicated that we had undertaken a program to determine to what extent that was true and that one particular measurement we were attempting was to measure adatom-adatom spacing distributions. In this paper we would like to present some further results and also discuss the general validity of our approach.At present, our specimens are made by depositing 5 μl of a 10-4 - 10-5 M solution of a heavy-atom-containing molecule onto a thin carbon film. The drop is allowed to sit for about 20 seconds and then pipetted off the film. This results in the heavy atoms being deposited within a molecule and so if the molecule remains intact, the preferential spacings between heavy atoms which may be observed could be dependent upon the molecule.