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These inter-laboratory control data provide a means for laboratories to review their performance on reproductive toxicity measures, and provide perspective for interpreting their own control data and data from treated animals.

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study to explore factors related to PA in CS in central Pennsylvania. Participants completed questionnaires assessing sociodemographics, the home environment for exercise, perceived neighborhood environment, walkability, and PA. Logistic regression models were used to examine the associations between environmental correlates and the likelihood of meeting PA recommendations (!150 minutes of moderate-to-vigorous intensity PA). Results: CS (n ¼ 258) completed a brief demographic questionnaire, and 215 (83.3%) participants opted to complete a more indepth questionnaire assessing the environment and PA. Nearly half of participants were prostate (21.9%) or breast (21.9%) CS, and 21.9% of participants reported multiple cancer diagnoses. Participants were mostly women (59.1%), in their mid-60s (M age ¼ 64.7 AE 12.0 years), overweight (M BMI ¼ 29.7 AE 6.8 kg/m 2), and self-rated their health as good or better (84.3%). Over half (62.0%) of CS reported meeting PA recommendations. More equipment in the home for exercise (OR ¼ 1.3, 95% CI: 1.1-1.6) and greater environmental support for PA (OR ¼ 1.3, 95% CI: 1.1-1.6) were associated with a higher likelihood of meeting PA recommendations, after adjusting for age, gender, income, BMI, and cancer type. In the adjusted multivariate model, meeting PA recommendations was associated with lower street connectivity (OR ¼ 0.5, 95% CI: 0.2-1.0), higher neighborhood aesthetics (OR ¼ 2.8, 95% CI: 1.1-7.1), and the home environment (OR ¼ 1.3, 95% CI: 1.1-1.6). Conclusions: Findings suggest that the home and neighborhood environment impact PA in rural CS and point to the need for interventions designed to meet the unique built environmental needs of rural CS in an effort to increase PA, improve cancer survivorship outcomes, and reduce cancer health disparities.