Introduction: Cytomegalovirus seroprevalance in developing countries is found to be high but there is no recent study done in India especially in children. Primary CMV infection is asymptomatic, but the virus remains latent in organs and children shed the virus in their urine and saliva for a long period. Primary infection can cause major consequences in growing fetus, premature infants, and immune deficient individuals especially those with AIDS. It highlights the need for sero negative blood for transfusion. Methods: This cross sectional study done in children of the age group 0 to 18 years, serum samples were collected randomly from the children and neonates were used for IgG anti-CMV antibody titration by ELISA kit. Data were analyzed by SPSS, Windows version 15. Chi-squar tests were applied. Result: The overall prevalence was 84%. The prevalence in age groups 1-28 days, 28 days to 1 year, 1-5, 6-10, 11-15, 16-18 years were 92.8%, 87.5%, 86.2%, 85%, 69.2%, 100% respectively. There was no statistically significant association between CMV sero prevalence and age, gender, residential area. Conclusions: Study shows a high prevalence of CMV infection in the age group especially chance of acquiring the infection drastically increases in the 1-5 years and 5-10 years population. High prevalence in neonates but relatively low prevalence in infants suggests maternal transmission rather than intrauterine infection. It is prudent to provide CMV screened blood products especially for preterms, immune deficient individuals.
Foreign body aspiration is an important cause of pediatric morbidity and mortality, particularly in children between the age of 6 months and five years. It is potentially life threatening event and may also cause chronic lung injury, if not properly managed. Foreign bodies may cause chronic pulmonary infections, bronchiectasis and lung abscess. An early diagnosis and management of the patient with an inhaled foreign body offers a diagnostic challenge to the treating pediatrician. We report a case of incidental foreign body in a 3year old child presented with recurrent episodes of wheeze associated respiratory tract infections. Wheeze was associated with persistent cough and dyspnea with nocturnal awakening.
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