Glaucoma is second leading cause of blindness in world. Various treatment modalities are available for glaucoma management. Thus, the question arises whether SLT can be interchangeably used in place of medical drugs or not. To examine the effect of selective laser trabeculoplasty (SLT) as a replacement therapy for medically controlled primary open-angle glaucoma (POAG) patients. A longitudinal study SLT was performed in 30 eyes of 15 patients with medically controlled primary open-angle glaucoma (POAG) cases from June 2018 to October 2019 and with no previous history of glaucoma surgery. Data were recorded 1 hr, 1day, 1 week, 1, 3 and 6 months after SLT. The primary outcome was number of medications at 6 months while maintaining a predetermined target intraocular pressure (IOP). Selective laser trabeculoplasty (SLT) reduced number of medications from a mean of 1.6 at baseline to 0.17 after 6 months. Meanwhile, SLT achieved more than 20% IOP lowering in 100% of eyes after 6 months. Eighty seven percent of our eyes no longer needed any medication after SLT at 6 months.Selective laser trabeculoplasty was able to completely replace medical therapy in 87% of eyes after 6 months. Medically managed POAG patients who underwent SLT, maintained good IOP control with less medications, better compliance, reduced side effects and financial burden.

High myopia is a risk factor for a number of retinal pathologies. OCT is very useful in eyes with high myopia and allows the detection of subtle macular changes that are otherwise undetectable. Aim: To evaluate relationship between the axial length, refractive error and macular thickness in subjects with high myopia. Study Design: Cross sectional observational single centric study. Materials and Methods: 50 diagnosed patients of high myopia(refractive error>= -6 dioptres and/or axial length>=24 mm) along with a control of 50 emmetropic patients were included. Patient's anterior segment evaluation was done by slit lamp. Detailed fundus evaluation was done with indirect ophthalmoscopy and with +78 Dioptre lens along with measuring BCVA (Best corrected Visual Acuity). Axial length was measured using contact biometry. OCT was performed with TOPCON SD-OCT. Average macular thickness, central foveal thickness and total macular volume measured using 3D macula scan of all the cases and controls. Statistical Analysis: Unpaired t test.Results: The mean axial length was 27.40 mm among cases (SD±0.99) and 22.84 mm among controls (SD±0.422). The mean macular volume in cases was 6.90 and in controls was 7.82. The macular volume decreased with increasing axial length (ρ=-0.673) and increasing spherical equivalent (ρ=-0.035). The average macular thickness was inversely correlated with axial length (ρ=-0.605) and directly correlated with spherical equivalent (ρ=-0.049).The mean central subfield foveal thickness was 170.10 µm amongcases and 158.34µm among controls. The axial length and central foveal thickness were found to be positively correlated (ρ=0.727). Conclusion: Average macular thickness and total macular volume are inversely correlated to the degree of myopia, whereas central foveal thickness is positively correlated to the degree of myopia.