For years, vitamin D has been associated to many immune disorders. Several studies have shown association between low serum 25 OH vitamin D and type 1 diabetes mellitus (T1DM).Objective: To compare 25 hydroxy vitamin D (25 OHD) level in T1DM patients to non-diabetic children hospitalized or seen in emergency for other diseases at the same period.Methods: It was a case-control study including 29 patients with T1DM and 28 non -diabetic control children. They were comparable in age, gender, weight, length, BMI and season of blood sampling. Epidemiological and clinical data were collected and 25OHD serum level was measured with a radioimmunoassay kit.Results: 25OHD level was significantly lower in diabetic patients (mean: 19.62 ng/ml, range 15-26 ng/ml) than in control patients (24.64 ng/ml, 20-28 ng/ml), p=0.00. All participants (T1DM patients and controls) had inadequate levels of vitamin D. Conclusion:Children with T1DM have lower vitamin D levels than control group.

No abstract

Wang Score = 10 (8 -12)  Delay between admission and initiation of HFNC therapy 5 hours (0 -48h)  Median initial flow rate= 6 l/min (6 -10 l/min)  Evolution:  Decreasing respiratory rate 2h after initiation of HFNC: 14 cases  Decreasing heart rate 2 h after initiation of HFNC : 10 cases  Secondary bacterial infection: 15 cases (50%)  Success of HFNC  18 cases (60%) Oxygen therapy by HFNC = 2.2 days (1 -9 days)  Failure of HFNC  ICU: 12 cases (40%)  Lenght of mechanical ventialation= 5 days (2 -6)  Lenght of ICU stay= 8 days (3 -12)  Lengh of hospital stay= 10 days ( 4 -21)  Skin lesions du to HFNC= 2 cases Predictive factors of HFNC therapy failure (p<0,05)

RESULTS 40 patients: boys=24 ; girls=16  Sex Ratio=1.5  Mean period of follow= 36 months  20 patients  persistent wheezers  20 patients transient wheezers  Epidemiology  Familial allergy  History of asthma  Socio-economic conditions and environment in persistant wheezers  bad socio-economic conditions n= 8 / p=0.97  Maternal smoking n=3 / p=0.63  Paternal smoking n=11 / p=0.89  Humidity n=13 / p=0.29