A B S T R A C T BACKGROUNDWild animal related injury is a serious health problem for people living in the foothills of the sub Himalayan terrain. Geographically the foothills are proximal to the tea gardens and the dense forests which in turn are in close proximity to human habitation. Thus, the tea garden workers and labourers as well as others are always at imminent threat from the abundant wildlife. The type of injury could be quite serious, sometimes grotesque and even life threatening. Though we regularly face various kinds of such injuries inflicted from wild animals, there are no studies regarding this very pertinent problem at hand. We wanted to evaluate the causes and treatment outcomes of wild animal injuries in the foothills of sub Himalayan terrain.

Introduction: The incidence of Oesophageal Adenocarcinoma (EAC) has increased at a faster rate than any other cancer in the developed nations. Despite advances in treatment, five year survival rate for EAC is <15%. Till date, Barrett’s Oesophagus (BE) is the only known precursor of EAC increasing its risk by greater than 30 to 60 fold. Most important risk factor for development of dysplasia and EAC is specialised Intestinal Metaplasia (IM) in BE. Aim: To find the association between clinical, endoscopic and histopathological features and presence of IM in patients with endoscopically suspected BE. Materials and Methods: This was an institution based descriptive study with a cross-sectional design conducted in the Departments of Pathology and Surgery, in a tertiary care centre of North Bengal for four years (2017-2021), among patients attending surgery and medicine Outpatient Department (OPDs) or Inpatient Department (IPDs), suspected on clinical basis and subsequent endoscopic detection of BE utilising Prague criteria. Periodic Acid-Schiff (PAS) and Alcian Blue (pH 2.5) stains were used to detect complete or incomplete IM and results were analysed using appropriate statistical software. Results: Among 120 cases included in the study, 72 (60%) had Short Segment Barrett’s Oesophagus (SSBE) and 48 (40%) Long Segment Barrett’s Oesophagus (LSBE). Hiatal hernia was significantly more frequent in LSBE patients (32 out of 48) compared to patients with SSBE (24 out of 72). The associations of tobacco and alcohol abuse with microscopically proven BE were statistically significant with p-values of 0.005 and 0.004, respectively. The association of IM with the increasing length of Columnar Lined Oesophagus (CLE) was statistically significant (p-value=0.004). Conclusion: Tobacco and alcohol abuse, presence of hiatal hernia (particularly in LSBE patients) were significantly associated with BE. Increasing length of CLE is more commonly associated with IM. Incomplete IM was observed more commonly in LSBE cases whereas complete IM was detected more frequently in cases diagnosed as SSBE by endoscopy

Background: Salivary gland tumors (SGT) are uncommon tumors of diverse histopathology accounting for <2% of all neoplasms. Early diagnosis differentiates between benign and malignant SGT and less extensive surgical procedure can be performed. The objective is to study the spectrum of primary SGT with special emphasis on their distribution, treatment and outcome at a rural tertiary care centre.Methods: A prospective observational study was conducted on 30 consecutive primary SGT patients attending the Departments of Surgery and Otorhinolaryngology of North Bengal Medical College and Hospital over a period of one and half years. All patients were clinically evaluated, investigated, treated accordingly and followed up during the period of study. Data was collected and compiled in Excel sheet and analysed using GraphPad Software and GraphPad QuickCalcs 2018 (San Diego, CA). A p value <0.05 was considered statistically significant.Results: Maximum patients (83.3%) were in the age range of 31-60 years. The male to female ratio was 1:4 for benign tumours and 1:1 for malignant tumours. Malignant cases were 66.67%. Involvement of parotid gland was the commonest (43.3%) and mostly presented with swelling (73.3%). Pleomorphic salivary adenoma was the commonest benign tumor (33.3%) and mucoepidermoid carcinoma was the commonest malignant tumor (16.7%). Permanent facial palsy was observed in 2 (9.5%) and recurrence in 4 patients (19%).Conclusions: SGT are rare and present in various modes. Malignant cases were singularly more in this study.

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BACKGROUND Colorectal Carcinoma (CRC) is an upcoming aggressive malignancy, especially among young adult population in recent years. This study emphasises on assessing disease burden and its outcome in young age colorectal carcinoma patients. The aim of this study is to assess aggressiveness of disease among all CRC patients and to evaluate, post treatment, patient's outcome in all age groups with special emphasis on young age (<40 years). MATERIALS AND METHODS A study of patients with features of CRC was conducted in a tertiary care hospital with systematic history documentation, preoperative examinations and post-operative follow-up. Statistical Analysis-Data was collected and compiled in Excel sheet followed by analysis using software Epi Info and Epi Calc 2000. Data was analysed using Z-test. Settings and Design-This is a descriptive type of study conducted for a period of two years. RESULTS Maximum CRC patients were in the age group of 30-40 years, mean age 47 years. Rectum was affected more than right and left colon. Ulceroproliferative is the most common morphology observed. Non-mucinous adenocarcinoma is the commonest microscopic variant seen. 16 cases (out of 62) of CRC presented to the emergency department. Patients presented mostly in advanced stage (stage III and IV). 30 of 62 patients received neo-adjuvant therapy. 45 cases went for complete pathological margin negative (R0) resection of carcinoma. Young patients (<40 years) needed more adjuvant therapy and had statistically significant increased incidence of recurrence and metastasis. CONCLUSION Incidence of CRC is remarkable among patients <40 years. It is comparatively an aggressive disease with poorer prognosis among young patients.