No abstract

Products formed in-vitro from ampicillin and amoxycillin penicilloates have been examined by high-performance liquid chromatography, ultraviolet and nuclear magnetic resonance spectroscopy and thiol group determination and were found to be the 5S epimers of the penicilloic acids. This is in contrast to a published claim that the corresponding penamaldic acids were formed by the treatment used.

No abstract

No abstract

A detailed study of the N-H stretching modes of a number of bases is reported and a correlation established between the solvent dependency of v(N-H) and the dissociation constants of their conjugate acids. It is proposed that the AV/V solvent slope be adopted as a measure of the intrinsic proton-accepting power of a base. Such values provide an acidity scale which is independent of solvent.Recent work ~2 has shown that the solvent shift of an infra-red-active hydrogenic vibrational frequency is primarily due to solute-solvent dipolar association, 40 d-8+ d-Pergamon Press), in press.