Purpose. To study the morphological features of the palatine tonsils of experimental animals in normal conditions and during the modeling of chronic tonsillitis. Material and methods. A model of experimental chronic tonsillitis was created on 15 rabbits, 5 animals were included in the control group. Chronic tonsillitis was simulated under general anesthesia. Staphylococcus aureus was injected into the palatine tonsils of animals in a dose of 3 million microbial bodies. Morphological studies of the tissues of the palatine tonsils of animals in the control group and the experimental group were carried out one month after modeling. Results. The results of a morphological study of the tonsils of the experimental group of rabbits clearly demonstrated manifestations of chronic tonsillitis (proliferation of connective tissue in the subepithelial layer, weakening of the muscle tone of the vessels with a simultaneous change in the permeability of the vascular wall, developing hyalinosis). Conclusion. Morphological studies of the tonsils have confirmed the similarity of the modeled chronic pathology with the disease of a similar human organ. Key words: palatine tonsils, rabbits, chronic tonsillitis model, morphological studies.
Purpose. Experimental study of tonsillogenic changes in the choroid and retina in an. Material and methods. Clinical and functional studies of the eyes of animals were carried out 3 months after modeling of chronic tonsillitis. Fundus images were photographed using RETCAM II (USA) wide-field digital pediatric retinal camera. Optical coherence tomography (OCT) was performed on 3D OCT-1000 MARK II optical coherence tomograph (Topcon, Japan). The functional state of the microhemocirculatory bed in the equatorial part of the eye was determined transscleral with laser Doppler flowmetry using LAKK-02 analyzer. Results. 3 months after the modeling of experimental chronic tonsillitis, dystrophic changes in the layer of nerve fibers, RPE dysfunction, and a reduced thickness of the own choroid persist. There is a deterioration in the functional state of the microcirculatory bed in the equatorial part of the eye. Conclusion. The use of optical coherence tomography, along with laser Doppler flowmetry, seems to be promising in assessing chorioretinal changes after modeling chronic tonsillitis. In the long term, after modeling of chronic tonsillitis, dystrophic changes in the layer of nerve fibers, hyperplasia of RPE cells, and a decrease in the thickness of its own choroid persist. There is a deterioration in the functional state of the microcirculatory bed in the equatorial part of the eye. Key words: chronic tonsillitis, laser Doppler flowmetry, retinal pigment epithelium, nerve fiber layer, choroid.
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