Incubation of cultured rabbit hepatocytes with p very low density lipoproteins (B-VLDL) induces a dose-dependent increase in cell cholesterol (CH) content and VLDL apoprotein (apo) B and E secretion without change in apo-B mRNA level. These data suggest that j?-VLDL may exert a stimulatory effect on hepatic apo-B production at the co-translational and/or posttranslational level.p-VLDL; Cholesterol; VLDL secretion; Apolipoprotein B; mRNA; (Rabbit hepatocyte)

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