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Objective To report the aetiological, diagnostic and therapeutic aspects of penile Mondor's disease treated with non‐steroidal anti‐inflammatory drugs (NSAIDs) or surgery. Patients and methods During the last 3 years, 10 patients (mean age 35 years, range 20–57) were treated for superficial penile vein thrombophlebitis. The main aetiological factors were prolonged and excessive sexual intercourse, operations for inguinal hernia and deep vein thrombosis. All patients had noticed sudden and almost painless cord‐like induration on the penile dorsal surface. Doppler ultrasonography was useful in both diagnosis and follow‐up. Eight patients were treated with NSAIDs and platelet drugs. Results The mean interval to resolution of symptoms was 3 weeks. Two patients who did not respond to drug therapy underwent surgery (dorsal vein resection). Conclusion Medical therapy and, when indicated, vein resection are successful and effective in treating penile Mondor's disease.

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