No abstract

Diarrhoea is one of the leading causes of morbidity and mortality in children under the age of 5 years. Due to this problem, the World Health Organization has encouraged studies that will bring about the desired treatment and prevention of diarrhoea. Myrianthus arboreus leaves (MA) is used in some tribes of Nigeria for food. In this study, the antidiarrhoea activities of the aqueous extract of Myrianthus arboreus leaves were investigated with experimental animals via feacal count, measurement gastrointestinal charcoal meal distance and electrolyte composition.  The extract (500, 1000 and 2000) mg/kg in comparison with loperamide hydrochloride, decreased the degree of gastrointestinal motility, production of diarrhoea stool, reduced the frequency of defecation and delayed the onset of diarrhoea in castor oil induced in albino rats. Also the extract inhibited the concentration of intestinal fluid electrolytes.

Aim:The study is to investigate the impact of Costus afer methanolic stem extract on lipid metabolic profiles and bilirubin levels in alcohol-induced liver cirrhosis progression in rats. Materials and Methods: Male wistar strain albino rats were randomly divided into five groups: Control (normal feed and water only), Costus afer control (CA), Ethanol control (Ethanol), ethanol + Costus afer (60mg) treated rats (CA + ETHANOL) and ethanol + Costus afer (120mg) treated rats (CACA + ETHANOL). Serum levels of lipids and bilirubin were measured. Results: The result showed that ethanol only administration caused triglyceride, cholesterol, low density lipoprotein and bilirubin to increase by 46.1%, 64.3%, 10.71% and 0.18% respectively compared to control rats (p<0.05). High density lipoprotein was shown to have decreased by 11.2% compared to the control.

Background: Thrombocytopenia occurring in falciparum malaria infection has been documented worldwide. However, its prevalence varies from place to place, and among different population groups studied. There is paucity of data on this in Nigerian children. Objectives: To determine the prevalence of thrombocytopenia in children presenting with falciparum malaria at the

No abstract