The authors reviewed records from consecutive patients in an MS clinic (n = 1,098) and in a uveitis clinic (n = 1,530) to select patients with "definite MS" and uveitis. A total of 28 of 2,628 patients (1%) were identified: 12 from the MS clinic (12 of 1,098; 1.1%) and 16 from the uveitis clinic (16 of 1,530; 1%). Pars planitis and panuveitis were most commonly encountered. The delay between the onset of neurologic and ocular symptoms (mean, 9 years) emphasizes the importance of a sequential diagnostic search throughout the patient's course.
A local synthesis of IgG antibodies against herpes simplex virus, cytomegalovirus, varicella-zoster virus and Chlamydia trachomatis was assayed for in aqueous humor and sera from 226 patients with various clinical types of uveitis. Comparison of the ratios of specific antibodies tested for in aqueous humor and serum (C′) and the evaluation of the Goldmann-Witmer coefficient (C) to each specific antibody were simultaneously studied in each case. The combination of these two methods allowed for the diagnosis of viral uveitis in 37.7% of selected uveitis patients and in 13.27% of randomized uveitis patients.
Lodoxamide 0.1% and levocabastine 0.05% eye drops, instilled four times daily for three months, were effective, safe and well tolerated by patients with VKC, but lodoxamide was significantly superior to levocabastine.
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