This report covers 38 Cases of intradural dermoids (4 cases) and epidermoids (34 cases). In most cases the clinical course extended over several years. At the time of admission to the clinic only 9 patients had purely local symptoms; symptoms from adjacent areas were present in 15 cases and elevated intracranial pressure in 13. Of the 35 operated patients, 16 were able to work again, and 7 died after the operation. Best results are achieved in cases involving young patients, in cases where the tumor is situated in the cerebral hemisphere, and in cases where the tumor can be totally removed. In recent years advances in diagnostic, surgical and anaesthetic techniques have lowered the lethality rate. Computed tomography is especially useful for an early diagnosis.

In order to answer the question of an opioid influence on consciousness, a radio-immuno-assay (n = 852) of beta-endorphin and beta-LPH (beta-lipotropic hormone) in both ventricular CSF and blood plasma was carried out in 101 neurosurgical patients. The following results were obtained: I) beta-END and beta-LPH levels were found to be lower in the CSF than in blood plasma. II) beta-END and beta-LPH in the CSF was the same in both sexes. III) beta-END levels in the CSF decreased with age. IV) beta-END and beta-LPH levels showed a diurnal rhythm with a maximum in the late a. m. hours. V) beta-END levels in the ventricular CSF tend to decrease parallel to a drop in conciousness as well as with longlasting comatous states. VI) beta-END in ventricular CSF becomes higher with increasing systolic arterial blood pressure. VII) beta-END and beta-LPH levels in ventricular CSF are not correlated with the type of the disease, CSF pressure, body temperature or respiratory changes.

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