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COVID-19 vaccine hesitancy and uptake among Southern states in the US has been problematic throughout the pandemic. To characterize COVID-19 vaccine hesitancy and uptake among medically underserved communities in Tennessee. We surveyed 1482 individuals targeting minority communities in Tennessee from 2 October 2021 to 22 June 2022. Participants who indicated that they did not plan to receive or were unsure whether to receive the COVID-19 vaccine were considered vaccine-hesitant. Among participants, 79% had been vaccinated, with roughly 5.4% not likely at all to be vaccinated in the next three months from the date that the survey was conducted. When focusing particularly on Black/AA people and white people, our survey results revealed a significant association between race (Black/AA, white, or people of mixed Black/white ancestry) and vaccination status (vaccinated or unvaccinated) (p-value = 0.013). Approximately 79.1% of all participants received at least one dose of a COVID-19 vaccine. Individuals who were concerned with personal/family/community safety and/or wanted a return to normalcy were less likely to be hesitant. The study found that the major reasons cited for refusing the COVID-19 vaccines were distrust in vaccine safety, concerns about side effects, fear of needles, and vaccine efficacy.

Essential Hypertension: Sir George Pickering, in a St. Cyres lecture to the Institute of Cardiology, discusses quantitatively certain features of essential hypertension and reviews the clinical picture of both its early and late stages (p. 959). Carcinoma of Thyroid: Professor D. W. Smithers and colleagues analyse 59 patients treated with radioactive iodine at the Royal Marsden Hospital (p. 969). Aorto-iliac Occlusion: Mr. J. H. Johnstone and colleagues consider that after surgical infrarenal aortic occlusion anoxic metabolites do not appear to be the cause of the systemic hypotension when the clamps are released (p. 974). Eczema and Keratoconus: Dr. P. W. Monckton Copeman reports a high incidence of eczema in patients with keratoconus, and suggests that excessive eye-rubbing may account for the conical distortion of the cornea (p. 977). Defibrination in Pregnancy: Dr. J. Willocks and Dr. J. MacVicar describe three patients whose symptoms were successfully reversed by fibrinogen (p. 979). Leader at p. 955. Fatal Chicken-pox: Dr. A. W. Blair and colleagues report deaths from encephalitis and other complications (p. 981). Leader at p. 954. T. glabrata Urinary Infection: Dr. L. Edebo and A. Spetz, of Sweden, discuss the therapeutic value of making the urine alkaline (p. 983). Incontinence Clamp: Dr. L E. Edwards describes one simple to operate (p. 985). Mothers in a Paediatric Unit: Dr. I. D. Riley and colleagues on admitting the mothers of ill children to a paediatric unit (p. 990). Commonwealth Medical Conference: Final communique (p. 993). Leader at p. 957. Surgical Infections: Prevention of infection in theatres and wards (p. 994). John Haddy James: Waterloo surgeon (p. 995). Pertinax: " Without Prejudice " (p. 996). Negotiations on Family Doctor Service: Reports of meetings of G.M.S. Committee and B.M.A. Council (Supplement, pp. 167 and 172). Indomethacin and Gastric Ulcer: Dr. F. Dudley Hart draws attention to gastric ulcer as side-effect of the drug (p. 1000). The Second Report: Letters on pp. 997-999. Dr. C. Hart writes, "I am convinced that the majority of us want the N.H.S. to survive. Dr. J. W. Maltby writes, "It is essential that

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