The distribution of serum calcium levels among postmenopausal women with incident breast cancer was shifted significantly toward the right. These findings are consistent with an effect of early breast tumors on calcium homeostasis. However, the lack of association between serum calcium levels and tumor size or stage supports the hypothesis that subclinical hyperparathyroidism may increase the risk for breast cancer.
This study evaluated the inclusion of butorphanol to an acepromazine maleate (ACP) premedication in 20 healthy bitches undergoing elective ovariohysterectomy to determine whether this was beneficial in improving the practice's premedication protocol. Ten bitches were administered ACP (0.04 mg/kg) and ten bitches were administered ACP (0.01 mg/kg) and butorphanol (0.01 mg/kg); both groups received carprofen (4 mg/kg). Anaesthesia was induced with propofol (4 mg/kg) to effect and was maintained on isoflurane. The time of extubation, sternal recumbency and standing was recorded, and pain scores were completed at 0, 1, 2, 3 and 24 hours. The volume of propofol required to induce anaesthesia was also recorded. Owners completed a questionnaire regarding the bitch's behaviour post operatively. It was concluded that the addition of butorphanol to an ACP premedication significantly increases the time for the bitch to regain sternal recumbency and to stand (p=0.017); all other differences in effects and observations between the two groups were statistically insignificant.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.