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The motto of the work investigates the synthesis of silver nano-particles by simple and economic green synthesis. With aid of citrus fruit that is lemon peel extract under different conditions, Characterization of silver nano-particles was carried out by using ultra-violet visible spectroscopy, X-ray diffraction, Fourier transferred infrared spectroscopy. The antimicrobial activities of synthesized silver nano particles (AgNPs) characterized by well diffusion method (WDM). Lemon peel extract mediated silver nano particles showed significant antimicrobial activity and have attention of pharmacists in order to design medicines. The results of antimicrobial test on the lung cancer cell has been witness the synthesis of drugs using extracted lemon peel is emerged as an eco-friendly, cost effective and most attentive synthesis.

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