In conclusion, there may be an inverse relation between severity of symptoms and level of Helicobacter pylori induced gastric inflammation or oxidative stress in patients with functional dyspepsia.

Background: The C-reactive protein (CRP) to albumin ratio (CAR) is a new index calculated by dividing CRP by the albumin level. It has been claimed to have predictive value in determining morbidity and mortality in many critical diseases Aim: In this research, we aimed to elucidate the importance of CRP, albumin, and CAR as parameters that can predict the clinical course in COVID-19 patients.Materials & method: In this retrospective analysis, the clinical, laboratory, and radiological findings of patients over the age of 18 who were diagnosed with SARS-CoV-2 infection with a positive reverse transcription-polymerase chain reaction (RT-PCR) test were evaluated. Age, gender, laboratory examinations at admission, and CRP and albumin values at the time of diagnosis have been recorded. The relationship of these parameters with the requirement for intensive care, exitus, and serious illness in the clinical follow-up of the patients was investigated. The baseline hospitalization parameters of the patients were compared between the severe and non-severe groups.Results: Individuals with severe disease had a higher rate of additional disease than those with non-severe disease. It was observed that the mean laboratory values of patients with severe disease had a statistically higher level of D-dimer, CRP, aspartate aminotransferase (AST), platelet distribution width (PDW), CRPalbumin ratio, and ferritin, compared to mild to moderate cases (p<0.05). The rate of additional disease in deceased patients was higher than in patients who were alive (p<0.05). The CAR value was found to be moderately predictive in our study revealing the severity of the disease, and the possibility that the severity of the disease might be higher in patients with a CAR value above 21.47. Conclusion:The results of this study revealed that CAR is a potential parameter in distinguishing critically ill COVID-19 patients in need of intensive care. Therefore, one can say that CAR is an important biomarker in clinically determining COVID-19.

Ground-glass hepatocytes are the cardinal biopsy feature of chronic hepatitis B virus (HBV) infection and may also be present in other specific conditions, including Lafora's disease, cyanamide aversion therapy for alcohol use, patients with transplantation, uremia, and metabolic disorders. In this report, we present the case of a patient with adult-onset Still's disease who underwent percutaneous liver biopsy, which revealed ground-glass-like cytoplasmic inclusions and which is a very unusual finding.

A AB BS S T TR RA AC CT T O Ob bj je ec ct ti iv ve e: : The purpose of this study was to determine the pathogenic agents in nosocomial infections and measure their antimicrobial sensitivity in the intensive care unit. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : Between January and October 2007, 250 patients were examined in the intensive care unit of the 1st Internal Medicine Department of Atatürk Training and Research Hospital, which was opened in January 2007. Active and prospective surveillance method based on laboratory data and patients' diagnosis was used for 95 of these patients with hospital-acquired infections. R Re es su ul lt ts s: : During the study period, 137 infection episodes were determined in 95 patients with a diagnosis of nosocomial infections according to the criteria of Centers for Disease Control (CDC). The infection rate was 38%. Urinary tract infection was the most common infection followed by pneumonia and bacteremia. All patients with urinary tract infection had urinary catheterization, 42.5% of the patients with pneumonia had mechanical ventilation and 68.4% with primary bacteremia had central intravenous catheterization. In these infections, 59.1% of the isolated pathogens were gram-negative bacilli, 38.6% were gram-positive bacteria and the remaining 2.1% were Candida spp. Escherichia coli, S. aureus, P. aeruginosa and coagulase-negative staphylococci were the most common pathogens identified. In urinary tract infections E. coli and in pneumonia and bacteremia S. aureus was the most common responsible pathogen. Among the gram-positive bacteria and gram-negative bacilli, high antimicrobial resistance was observed. Resistance to teicoplanin was 14.6% and linezolid was 11.1%, in S. aureus, whereas resistance to ciprofloxacin was 88.8% and vancomycin was 11.1% in Enterococcus spp. Imipenem was determined as the most effective agent against the isolated gram-negative bacteria, followed by cefepime, however, 16.6% of the Acinetobacter spp. and 17.6% of the P. aeruginosa were resistant to imipenem. C Co on nc cl lu us si io on n: : In order to prevent or reduce the nosocomial infections, surveillance methods must be carried out in intensive care units and in the entire hospital.K Ke ey y W Wo or rd ds s: : Intensive care units; cross infection; anti-bacterial agents Ö ÖZ ZE ET T A Am ma aç ç: : Bu çalışmada, yoğun bakım ünitemizdeki nozokomiyal enfeksiyonların patojen tiplerini belirlemek ve antibiyotik duyarlılıklarını ölçmek amaçlandı. G Ge er re eç ç v ve e Y Yö ön nt te em ml le er r: : Atatürk Eğitim ve Araştırma Hastanesi'nin Ocak 2007 tarihinde hizmete açılan 1. Dahiliye Kliniği Yoğun Bakım Ünitesinde, Ocak-Ekim 2007 tarihleri arasında toplam 250 hasta takip edildi. Bu hastalardan hastane enfeksiyonu tanısı alan 95 hasta için aktif, ileriye dönük, hasta ve laboratuar bulgularına dayalı sürveyans metodu kullanıldı. B Bu ul lg gu ul la ar r: : Çalışma sürecinde Hastalık Kontrol ve Önleme Merkezi (CDC) kriterlerine uygun olarak nozokomiyal enfeksiyon teşhisi konulan 95...

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