Although several pathophysiological mechanisms are defined in etiology recurrent pregnancy loss, still causes of half of the cases haven’t revealed yet. It is reported that inflammatory processes take place in the etiology of the disease. In our study, we aimed to reveal the relationship between recurrent pregnancy loss with white blood cell count (WBC), C-reactive protein (CRP) and ferritin levels. We included our study 90 pregnant women having recurrent miscarriage history and 101 pregnant women without recurrent miscarriages, 191 patients in total. Maternal and gestational age, height, weight, body mass index (BMI), gravidity, parity, abortion and living children count and WBC, CRP and ferritin levels of these pregnant were evaluated retrospectively. According to outcomes, while the age (p = 0.01; p<0.05), gravidity (p = 0.00; p<0.01) and abortion counts (p = 0.004; p<0.01) of the study group were found significantly to be higher than that of the control group, weight measurement of them was significantly lower than that of the control group (p = 0.04; p <0.05). Height and BMI measurements, parity and living children counts of the groups showed no statistically significant difference (p>0.05). While WBC levels of the study group was found to be lower (p=0.045, p<0,05) than that of control group, there was no significant difference regarding ferritin and CRP levels (p> 0.05). In our study, WBC, CRP and ferritin parameters did not indicate the inflammatory background in recurrent pregnancy loss. We think that further prospective randomized controlled studies are required regarding these parameters.
Objective: Increasing incidence of obesity in our country and all over the world and due to concomitant diseases has become a national health problem. Obesity is described as excessive fat accumulation and storing in the body and according to World Health Organization data on 300 million people are affected. Obesity is an independent risk factor for cardiovascular diseases and obese patients often carry increased risk for the development of hypertension, dyslipidemia and Type 2 diabetes. Weight reduction provides an improvement in obesity related comorbid conditions. For this purpose, to determine the effectiveness of diet in the prevention of obesity-related cardiovascular risk factors and in order to see the effects of diet on 10-year risk of cardiovascular disease, a prospective and observational clinical study was performed in Mersin University Family Medicine clinic between January and August 2014 with 178 female cases presented with obesity. Methods: Cases were followed with the six-month diet for obesity treatment. At the first advent of cases and 6 months after treatment with diet, staging of obesity according to waist circumference and body mass index, staging of blood pressure and laboratory data (lipid profiles) were performed and 'Framingham Heart Study' based on the results generated seven parameters (age, sex, blood pressure, LDL-cholesterol, HDL-cholesterol, cigarette use, diabetes and whether they are) scoring system using the 10-year cardiovascular risk were calculated. Results: After dietary treatment of patients, significant reduction in staging and laboratory data could not be detected but within 10 years of cases a significant reduction in the risk of developing cardiovascular disease was found. Conclusion: In obese patients, obesity and associated parameters we are able to provide small improvements in the unseen as significant, even for these cases, our rates of protection from the risk of cardiovascular disease can be quite significant.
Objective: In our study, we aimed to determine vitamin D levels among obese patients registered to Obesity Center and to investigate its relationship with body mass index (BMI). Methods: The study was conducted in the Obesity Center of Health Sciences University Samsun Training and Research Hospital. Records of 102 patients with BMI> 30 kg/m², 18 years of age and over, admitted to the obesity center between 01.12.2018 and 01.12.2019 were retrospectively analyzed. Serum 25-OH D level<20 ng/ml was accepted as severe insufficiency, 20-30 ng/ml insufficiency, >30 ng/ml proficiency. Mann-Whitney U, Pearson chi-squared and Spearman tests were used in the evaluation of the data. The data were evaluated by the SPSS 22.00 program. p<0.05 was considered significant. Results: A total of 102 patients participated. The mean age was 48.82±12.09 years. 62.75% of them were female. 24.51% of participants were class 1 obese, 32.35% of participants were class 2 obese, 43.14% of participants were class 3 obese. The prevalance of severe vitamin D insufficiency was 45.10% and insufficiency in 38.24% of the patients. The mean vitamin D levels of the patients registered to the Obesity Center was 13.26±7.74 ng/ml. The mean BMI was 35.26±4.28 kg/m². Serum 25-(OH)D levels were inversely related to BMI. There was a significant relationship between age and BMI (p=0.036). Conclusion: Vitamin D insufficiency is highly prevalent in obese patients registered to Obesity Center. Serum 25-(OH)D levels were inversely associated with BMI. Obese patients should be evaluated and followed for vitamin D insufficiency.
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