No abstract

A new infectious disease responsible for the emergence of respiratory syndrome and caused by the virus called coronavirus (SARS-CoV-2) was detected in late 2019 in Wuhan. Coronaviruses are a group of viruses, belonging to the family Coronoviridae of the order Nidoviridales and are responsible for causing, mainly, respiratory and gastrointestinal tract infections. SARS-CoV-2, despite predominantly infecting birds, has been responsible for the third major coronavirus outbreak in the last 20 years. In March 2020 the World Health Organization (WHO) declared the outbreak of COVID-19 cases to be a pandemic, and in October of the same year more than 1.04 million deaths were recorded.

It is known that emotions are part of the human being, directly influencing the immune system and in today's society stress is considered as one of the biggest problems in people's lives. Communication of the brain-intestine-microbiota axis may have altered functions for several reasons, including a change in the intestinal microbiota. This article aims to discuss the relationship between the digestive system and emotions. This is an integrative review of the literature. Stress induces changes in the microbiota, such as the predominance of a bacterium over other phylum's, which may affect the behavior of the brain, inducing the release of inflammatory cytokines that damage the brain neurochemical, leaving the individual more susceptible to anxiety and depression, which may clarify the association between inflammatory bowel disease and mental disorders. It is evident that there is a relationship between the digestive system and emotions, as well as with the normal microbiota and the immune system, through the gut-brain-microbiota axis.

Forensic toxicology is an important tool in the materialization of crime since it is verified the presence of toxic substances that will influence the elucidation of events related to the facts investigated, such as the performance of individuals who were involved in a traffic accident, or substances that have been the cause of death. This is a bibliographic review study, that is, a survey of theoretical framework from scientific publications, this at national and international level involving the performance of the pharmacist in forensic toxicology and its importance the data collection occurred through the Coordination for the Improvement of Higher Education Personnel (CAPES) and Google Scholar. It is understood, therefore, that professionals of the forensic sciences should have continuous training, as well as guidance and ethical and legal training focused on the dilemmas and specific cases of their functions seeking to prevent biases and biases.