The aim of this research was to analyze the anti-oxidant activities of ethanol extract of mahogany seeds on the liver tissues of diabetic experimental rats to overcome oxidative stress condition. This study used male Rattus norvegicus strain Sprague Dawley which were divided into 5 groups: (i) negative control group (K-), (ii) positive control group/diabetes mellitus (DM) (K+), (iii) DM group treated with 500 mg/kg BW ethanol extract of mahogany seeds (EM), (iv) DM group treated with acarbose (KO), and (v) non-DM group treated with 500 mg/kg BW ethanol extract of mahogany seed (KE). Alloxan with dose of 110 mg/kg BW was used to induce diabetes in rats. The treatments were conducted for 28 days. At the end of treatment, the liver tissues were collected and analyzed for malondialdehyde (MDA) content using thiobarbituric acid reactive substance (TBARS) method and anti-oxidant cooper zinc superoxide dismutase (Cu,Zn-SOD) content using immunohistochemical technique. The result showed that level of MDA were significantly different (P<0.05) in K-; K+; EM; KO; and KE with values were 0.81±0.17; 1.19±0.26; 1.10±0.04; 0.95±0.13; and 0.92±0.0 µmol/gram, respectively. The anti-oxidant content (Cu, Zn-SOD) of rat liver tissue in K+ lower than in K-, while anti-oxidant content in EM and KE were higher compared to K+. The study concluded that ethanol mahogany seeds extract decreased blood glucose levels and increased the anti-oxidant status in the liver tissues of diabetic rats.
Setiap rumah penduduk yang bertempat tinggal khususnya di kawasan perumahan memiliki tandon air sebagai tempat penyimpanan air, sebagaimana kondisi yang ada juga pada perumahan yang berada di lokasi perumahan xyz di wilayah cileungsi. Permasalahan yang ada pada tandon air di perumahan kurangnya pengontrolan diantaranya kondisi mesin pompa, kelistrikan, pipa saluran rusak atau lepas jika dibiarkan akan menyebabkan air akan terbuang secara percuma, selain itu juga tidak bisa monitoring kerusakan pada komponen peralatan mesin. Untuk mempermudah pengontrolan pada mesin dan peralatan mesin, pipa penyaluran air dan kondisi tandon air perlu sistem yang otomatis radar pintar berbasis Arduino Uno R3 menggunakan model ESP8266 merupakan sebuah microcontroller yang bisa untuk mengintegrasikan pengontrolan ketinggian air di tandon, sensor kerusakan mesin, kelistrikan, perpipaan, pendeteksian kerusakan, kelebihan sistem ini dapat di kontrol berbasis Internet of Things atau IoT. Setelah dilakukan pengujian secara keseluruhan sistem dapat berfungsi dengan baik dan mudah untuk dipergunakan dengan biaya pembelian komponen relatif murah. Sehingga sistem radar pintar ini dapat bermanfaat untuk pengontrolan tandon air untuk warga di perumahan
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