Essential oils are volatile, complex products of plants as secondary metabolites and include terpenes and their oxygenated derivatives, such as alcohols, aldehydes, esters, ketones, phenols and oxides. In recent years, out of 3000 essential oils obtained from plant origin only 300 essential oils have gained extensive attention for applications in various fields. In this review, we discuss the major biological activities associated with EOs as antimicrobial, antispasmodic, antioxidant, antiviral, anti-inflammatory, anthelmintic, insecticidal, antiparasitic, and cytotoxic agents. Different routes for delivery of essential oil along with the problems associated with essential oils like high volatility, low stability, permeability, bioavailability, poor water solubility, susceptibility to oxidation, decomposition, photosensitization and skin irritation are also highlighted. Furthermore, strategies to solve the mentioned problems are suggested by different nanoencapsulating systems. These include polymer-based nanocarriers, lipid-based nanocarriers and molecular complexes. It is believed that nanoencapsulation of essential oils will improve their therapeutic activity and delivery.
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The vast majority of people continue to view medicinal plants as a low-cost source of medications and treatments. Numerous trees, herbs, plants, and shrubs have been used as remedies for various ailments since the dawn of time. Rubus ellipticus Smith, a weedy wild raspberry that flourishes in damp woods at high elevations, particularly those in the Himalayas and the Nilgiris area, is one of the important ethnomedicinal plants in the genus Rubus. Traditional Tibetan medicine places a great deal of importance on the plant R. ellipticus. Because of the abundance and diversity of phenolics and flavonoids in fruits or berries, which have a high concentration of both, they are generally regarded as inherently healthful foods. The roots and leaves, as well as the fruit, have traditionally been used as therapeutic agents for several illnesses including colic pain, gastrointestinal discomfort, wound healing, diarrhea, antifertility, antibacterial, analgesic, epilepsy, and others. The objective of the current review is to concentrate on the pharmacological characteristics, nutrition profile, phytoconstituents, and folkloric therapeutic applications of R. ellipticus, therefore achieving the review's overall subject.
Over 100–1000 microbial species reside in the human gut, where they predominantly influence the host's internal environment and, thus, have a significant impact on host health. Probiotics are best characterized as a microbe or a group of microbes that reside in the gut and support the body's internal microbiota. Probiotics are linked to increased health advantages, including better immune function, improved nutritional absorption, and protection against cancer and heart-related illnesses. Several studies have demonstrated that combining probiotics from different strains with complementary activities may have synergistic advantages and aid in re-establishing the equilibrium of how immunological niches and microorganisms interact. Another thing to remember is that even though a product contains more probiotic strains, that doesn't always guarantee that the health benefits will be more significant. For specific combinations to be justified, there must be clinical proof. The clinical results of a probiotic strain are specifically pertinent to the participants in the relevant research, such as studies on adults or newborn infants. Clinical outcomes of a probiotic strain are mainly connected to the investigated health area (such as gut health, immune health, oral health, etc.). As a result, picking the right probiotic is essential yet tricky because of several factors, including probiotic products with the disease and strain-specific effectiveness exists; however, various probiotic strains have diverse modes of action. The current review focuses on probiotic categorization, their function in enhancing human health, and any potential health benefits of probiotic combinations.
Background Rodents are the most common and diverse order of mammals, the most troublesome pest in agriculture, gardening, forestry, and public products, and to blame for the spread of many illnesses to humans and animals. In terms of rodenticidal exposure, rodenticide use is only to kill the rodent, not to repel it. On the other hand, herbal rodent repellents are compounds that, by taste, odour, or both, keep rodents away from human habitat and prevent diseases spread due to them. Herbal rodent repellents are more potent, economical, biodegradable, and do not persist in the soil or water, and they also have a broad range of other biological properties. Main body of the abstract Rodents are a prevalent and harmful pest that accounts for more than 2277 species distributed all over the world. The growing public awareness of the ethical and animal welfare problems associated with traditional pest animal control methods has progressively switched to non-lethal alternatives for the management of rodents. This article promotes herbal rodent repellents due to the various reported toxic effects of synthetic rodenticides on human health and the environment. The review discusses some of the important herbs that have the potency to repel rodents thereby raising awareness for the use of non-toxic methods for pest control. Data from different database like PubMed, Google Scholar, Research Gate, PLOS One, and others were retrieved, and then, an extensive literature review was carried out to prepare the article. Short conclusion From the information provided, it can be concluded that rodenticide poisoning could cause a serious public health issue with a high case death rate. Increasing public understanding of rodenticide toxicity, as well as stringent monitoring of rodenticide sales and use, might assist to reduce indiscriminate use and poisoning. Therefore, herbal rodent repellents, due to their least toxicity, could provide a safe and dynamic approach over the use of synthetic rodenticides.
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