Renal angiomyolipoma (AML) is the most common benign tumor of the kidney. There are few case reports in the literature, especially those occurring during pregnancy. We, at this moment, are reporting a case of a 32-year-old female patient who presented at 21 weeks of gestation with right-sided flank pain, chills, macroscopic hematuria, and vomiting. On examination, she was hemodynamically stable, with no fever. Renal ultrasound showed the presence of a hyperechogenic vascularized fatty tissue on the right kidney, measuring 7.4 x 5.1 x 6.2 cms, with minimal pelvicalyceal dilatation. The MRI opted for an angiomyolipoma. Discharged home at day 4 of admission, the patient’s continued the remaining weeks of her pregnancy uneventfully, until 37 weeks. She delivered her baby vaginally with no further complications during pregnancy or in the post-partum period.In conclusion, due to the insufficient data in the literature supporting the management of patients with AML, the individualization of the treatment is an essential strategy.

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Vaginal Penetration Disorders (VPD) consist a major sexual disorder that has a significant impression on young ladies and couple's relationships and also consist of a predisposing factor for anxiety disorders. All existing treatments of vaginismus are still a big challenge and often without success. Before performing PRP patients were referred to the gynaecologist, urologist or psychologist. Almost in every case after several attempts to be treated, they were disappointed with the results. Often, they have admitted to accept their problem and keep suffering because no physician could offer any effective help with significant results. We are reporting in this article a serie of ten cases where the Platelet Rich Plasma (PRP) treatment was tried based on their voluntary participation due to particular and relative sexual problems. Based on the results that are exposed here, we can say that PRP clearly has a positive effect not only on rejuvenation of the female genital structurebut also on improving VPD symptoms. It reduces pain, reduces mucosal dryness and chronic fissuration. The duration of the effect on the vaginal structure as well as clinical improvements requires more case studying and research. These patients will be evaluated for the coming 2 years to acquire more data to be analyzed in order to complete our observational study. It is nothing but the beginning of a new era in the sexual dysfunction therapy.