No abstract

Background The management of feline hindlimb full-thickness skin defects is challenging. On the other hand, the use of a semitendinosus (ST) myocutaneous flap for their coverage has not been reported. Objectives To describe the ST flap and compare it with second intention healing for managing hindlimb full-thickness skin defects. Methods In 12 purpose-bred laboratory domestic short-haired cats, two wounds were made on each tibia. The wounds in group A (n = 12) were covered with ST flaps, and those in group B (n = 12) were left to heal by second intention. In both groups, clinical assessment scoring and planimetry were performed between one–30 d postoperatively. Computed tomography-angiography (CTA) was performed on days zero, 10, and 30, and histological examinations were performed on days zero and 14 and at 6 and 12 mon postoperatively. Results Statistically significant differences in the clinical assessment scores were observed between groups A and B on days 14 ( p = 0.046) and 21 ( p = 0.016). On the other hand, the time for complete healing was similar in the two groups. CTA revealed significant differences in the muscle width (day 0 compared to days 10 and 30 [ p = 0.001, p = 0.026, respectively], and days 10 to 30 [ p = 0.022]), ST muscle density, and the caliber of the distal caudal femoral artery and vein (day 0 compared to day 10 [ p < 0.001], and days 10 to 30 [ p < 0.001]). Histologically significant differences in inflammation, degeneration, edema, neovascularization, and fibrosis were observed on day 14 compared to zero and 6 mon, but no differences were found between the time interval of 6 and 12 mon. Conclusions An ST flap can be used effectively to manage hindlimb full-thickness skin defects.

This work describes the preparation, characterization and functionalization with magnetic nanoparticles of a bone tissue-mimetic scaffold composed of collagen and hydroxyapatite obtained thorough a biomineralization process. Bone remodeling takes place...

ABSTRACT. Skin defects on the lower limb are common and their management is usually challenging. All trauma patients should be initially assessed for concurrent injuries and stabilized. Debridement and cleansing is performed in all wounds. The most important factors for decision making on wound closure are the wound size, the extent of soft tissue damage, the presence of contamination and impaired perfusion. Primary closure is the preferred choice although; it is seldom applicable in wounds on the distal limbs. Delayed primary closure, secondary closure or second intention healing can be undertaken under certain circumstances in such wounds. When these options are not feasible local pedicle flaps, axial pattern flaps, distant flaps, grafts, muscle or myocutaneous flaps and microvascular free tissue transfer can provide coverage.Keywords: cat, dog, limbs, skin defects ΠΕΡΙΛΗΨΗ. Τα ελλείμματα δέρματος στο περιφερικό τμήμα των άκρων είναι πολύ συχνά και η αντιμετώπισή τους αποτελεί πρόκληση για τον χειρουργό. Αρχικά, οι ασθενείς πρέπει να ελέγχονται για την ύπαρξη συνοδών τραυμάτων και να σταθεροποιούνται. Στη συνέχεια θα πρέπει να γίνεται νεαροποίηση και καθαρισμός όλων των τραυμάτων. Η επιλογή της κατάλληλης τεχνικής για τη σύγκλειση του τραύματος καθορίζεται κυρίως από τους εξής παράγοντες: το μέγεθος του τραύματος, τον βαθμό κάκωσης των μαλακών ιστών και την παρουσία επιμολύνσεων και διαταραχών της αιμάτωσης. Αν και η κατά πρώτο σκοπό σύγκλειση είναι η μέθοδος εκλογής σπάνια μπορεί να εφαρμοστεί σε τραύματα στο περιφερικό τμήμα των άκρων. Η καθυστερημένη κατά πρώτο σκοπό σύγκλειση, η κατά τρίτο σκοπό σύγκλειση και η επούλωση κατά δεύτερο σκοπό μπορούν υπό προϋποθέσεις να βρουν εφαρμογή σε ελλείμματα στο περιφερικό τμήμα των άκρων. Ωστόσο, σε περιστατικά όπου η παραπάνω επιλογές δεν είναι εφικτές μπορούν να εφαρμοστούν τοπικοί ή απομακρυσμέ-νοι κρημνοί, αξονικοί κρημνοί, μυϊκοί ή μυοδερματικοί κρημνοί, μοσχεύματα και μεταφορά ιστών με μικροχειρουργική.

No abstract