Background Basidiobolus ranarum belongs to the Entomophthorales order and the Zygomycetes class. This fungus is an environmental saprophyte that can be found in soil and rotting vegetables.Primarily restricted to tropical regions including Asia, Africa, and South America. It might cause chronic inflammatory diseases, mostly affect subcutaneous tissue. Systemic infections involving the gastrointestinal tract are extremely rare. Case presentation Herein, we present a 44-year-old Persian man with the past medical history of lupus erythematosus with colicky abdominal pain started from three months before admission with many vomiting episodes, and a mass on the right lower quadrant, who had been thought initially to have an abdominal malignancy. The patient had vital signs were within normal ranges. His physical examination revealed tenderness and rebound tenderness on the right lower quadrant of the abdomen. A fixed mass 10 × 10 centimeter in diameter was palpated in the same quadrant. Laboratory, radiologic, colonoscopic examination was requested. The patient underwent laparotomy which revealed a mass in the terminal ileum and ascending colon with retroperitoneal adhesion and invasion to the right ureter behind it. Pathologic examination showed basidiobolomycosis infection in the specimen. Conclusion Fungal infection should be among the differential diagnoses for adults present with abdominal mass in endemic regions of the world.
Background: Various studies suggest that coinfection with two or more respiratory pathogens is common. Coinfection with two viruses affects the host and exerts synergic effect as well and can influence the disease pathogenesis, immune system responses and treatment and outcome. Influenza and COVID-19 respiratory viruses have very similar symptoms and for this reason, bring about problems including delayed treatment and right diagnosis. This report describes three cases of coinfection with COVID-19 and influenza. Case Presentation: First case is a 46 years old Iranian housewife with the history of chronic coughs from two months ago who presented with exacerbation of coughs together with dyspnea. The second case is a 62 years old Iranian housewife with history of diabetes mellitus type 2 (DM-2) who presented with productive coughs, dyspnea and weakness. The third case is an Iranian pregnant housewife who presented with myalgia, fever and chills and dry coughs from a week ago. All three cases were tested positive for influenza and COVID-19 PCR tests. Conclusion: coinfection with two viruses can result in synergism of pathogens. Moreover, coinfection with a bacterial pathogen can make further problems. In these cases, coinfection with two viruses and mycobacterial infection in one of the cases along with comorbidities and pregnancy implied that these conditions entail immediate diagnosis as well as appropriate treatment choices.
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