Epidermolysis bullosa (EB) is a rare genetic disorder characterized by the formation of blisters and wounds in skin and mucous membranes; it is classified into four types and has various methods of treatment. Management of previous wounds and prevention of formation of new lesions are the most important strategies in the course of therapy to improve patient's quality of life; lack of wound management can lead to further complications such as infection. The current study investigated the therapeutic effects of allogeneic platelet gel (prepared from umbilical cord blood) in a group of children diagnosed with dystrophic epidermolysis bullosa (DEB) eligible for surgical correction of pseudosyndactyly in the hand. The post‐surgical clinical outcome in this group was compared with the clinical outcomes of DEB patients receiving the standard treatment (paraffin gauze wound dressing and topical antibiotics) after corrective surgery. The current study results showed an increase in the rate of recovery and promotion of tissue granulation, complete wound healing, and a decrease in pain level and treatment period. The application of cord blood platelet gel topical dressing was not a conventional method of treatment in patients with DEB wounds and blisters. However, the current study results demonstrated that this gel dressing could effectively accelerate epithelialization and healing of the wounds and decrease patients' pain and post‐surgical recovery period, which altogether leads to improvements in patients' overall quality of life.

Background People with acne scar suffer from destruction to the surface of the skin. Treating acne scars is a challenge that might need several methods. Aims Subsection is a method that has been informed to be a useful method in treating rolling acne scars. While Subcision is a valued procedure, its effect is mild to moderate due to its high reappearance rate, and patients' dissatisfaction with some of the side effects such as inflammation after procedure. Patients/Methods In this pilot study, 9 rolling acne scar patients underwent Subcision with the Endolift (200‐nm fiber) and followed up for 3 months. Outcomes were evaluated by 3 dermatologists (Blind). Also, the patients’ satisfaction was assessed to compare with dermatologist's opinions. Results Our results indicated that Subcision with the Endolift displayed good and very good improvement in about 90% of patient with a good and very good satisfaction in the patients. Photographic data evaluation indicated 100% improvement in scar depth, topography, and total acne scar appearance. The average numbers of lesions before the treatment were 25.5 ± 12.1, and after treatment, it was reduced to 11.4 ± 2.1 (P < .05). Conclusion Subcision with the Endolift seems to be a safe and effective method for acne scar treatment. It is done with a single perforation on each side (instead of several perforations), which reduces the pain and scar risk in the patients. Also, Endolift‐based Subcision needs fewer surgical sessions and less recovery time with less inflammation and erythema.

Periorbital hyperpigmentation (also recognized as periorbital melanosis, dark eye circles, and infraorbital darkness) is public cosmetic skin disorder with relative darkness of the periorbital. This condition is affected both sexes, they get worse by aging so it makes people look tired and older so it has a negative effect on the quality of life, particularly in women. 1 Many exogenous and endogenous reasons are overly involved in the pathogenesis of periorbital dark circles, containing genetics or heredity, facial structure, hyperpigmentation secondary to allergic and atopic contact dermatitis, troubled sleeping, smoking, alcohol drinking, and sun exposure can play a role in the development of these dark circles. 2 Several treatments are recommended for periorbital hyperpigmentation. However, there are