This research involved six nursing courses located in the South of Brazil and aimed to find out and evaluate the quality of life of the students. The model WHOQOL Bref model of the World Health Organization was adopted for data collection and analysis and revealed sensitivity for the intended diagnosis. The results indicated that 64% of the students mention satisfaction with their quality of life, but 36% present significant problems, which demand specific needs and justify the implantation of support programs to face the situations of suffering.