Introduction:The Zika virus has the ability to tropism in neuronal cells of fetuses, congenitally causing neurological disorders. Objective: To discuss the relationship between congenital Zika virus infection and the onset of congenital neurological abnormalities in newborns, including their neurological manifestations, and their impact on quality of life. Methods: Bibliographic review developed from October to November 2022, with searches in the PubMed and LILACS databases, 15 articles being selected after applying inclusion criteria. Discussion: Infections in the first trimester of pregnancy are those that result in serious malformations, which reinforces the importance of adequate prenatal care. The diagnosis of infection during the gestational period consists of serological and ultrasonographic examinations. The main manifestation observed intrauterine and after birth was microcephaly, which is characterized by the interruption of brain growth, with little cortical differentiation. However, changes in sensory organs can also occur. Final considerations: The studies demonstrate advances in the screening of such changes through possible radiological and laboratory changes during prenatal care, and also through postnatal neuroimaging tests.
Objetivo: Analisar a produção científica atual acerca do diagnóstico relacionado ao comprometimento cardíaco em pacientes pediátricos com síndrome inflamatória multissistêmica (MIS-C) associada ao Covid-19. Métodos: Trata-se de uma revisão bibliográfica integrativa, com busca em três bases de dados, Pubmed, Lilacs, SciELO, através dos descritores em inglês “Multisystem Inflammatory Syndrome”, “Pediatric”, “Covid-19”, “SARS-CoV-2” e “Diagnosis”, utilizado como critério de inclusão estudos publicados nos últimos cinco anos. Foram encontrados 950 estudos e selecionados, após os critérios de inclusão, 13 artigos para compor o estudo. Resultados: Entende-se o comprometimento cardíaco de pacientes pediátricos no contexto de MIS-C pós Covid-19, com consequentes condições hiper inflamatórias sistêmicas como choque, arritmias, risco de anormalidade da artéria coronária ou até mesmo dilatação e aneurisma da artéria coronária. Os parâmetros laboratoriais, que podem ser utilizados no diagnóstico complementar, são compatíveis com uma resposta inflamatória severa. Orienta-se o manejo adequado com tratamento farmacológico, priorizando o acompanhamento a longo prazo para evitar novas complicações. Considerações finais: Considera-se que os pacientes pediátricos com diagnóstico de MIS-C associada a Covid-19 apresentam graves complicações cardíacas, mas com prognóstico positivo se diagnosticados precocemente.
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