Taenia solium taeniasis (taeniasis) and cysticercosis in human are infectious diseases caused by pork tapeworm Taenia solium. They are zoonotic diseases and still a health problem in the world, especially in developing countries such as Indonesia. The prevalence of taeniasis and cysticercosis in Indonesia is still quite high at 2% - 48% with the highest prevalence in Papua. Human taeniasis can manifest as a asymptomatic or intestinal minimally symptomatic. Cysticercosis can involve of neural tissue (neurocysticercosis) may manifest epilepsy seizure, headache, neurological symptom, cognitive disabilities, and death. The habit of eating raw or undercooked pork, lack of sanitation, and a lack of supervision the slaughterhouse are some of the factors causing taeniasis and cysticercosis in human. Avoiding eating raw pork, cooking meat over temperature 54oC, supervision at slaughterhouses, and maintaining hygiene is a way to prevent taeniasis and cysticercosis, therefore it is necesarry to do more intensive programs to prevent and control the diseases.
Background: Dengue hemorrhagic fever (DHF) is a significant health problem. The high number of cases requires preventions, including controlling the dengue vector, Aedes aegypti mosquito. One of the control methods is the use of insecticides containing organophosphate. This study aims to detect organophosphate resistance in Aedes aegypti from DHF endemic subdistrict, Riau, Indonesia by a sensitivity test of temephos and 5% malathion and measuring the activity of non-specific alpha and beta esterase enzymes. Methods: This observational study determined Aedes aegypti resistance from larvae to adult in one DHF endemic subdistrict in Riau, Indonesia. The bioassay was used for temephos sensitivity of Aedes aegypti larvae. The LC99 value was analyzed using probit and compared with the diagnostic value from WHO. The WHO susceptibility test was conducted to determine 5% malathion resistance from adult mosquitoes. The mortality of less than 90% was declared as resistant. Measurement of alpha and beta esterase levels used Lee's microplate assay technique based on visual identification and absorbance value (AV). Results:The results showed that Aedes aegypti were resistant to temephos. It also showed that adult mosquitoes were resistant to 5% malathion. Based on the alpha esterase activity test, it was found that most of the mosquitoes showed very sensitive meanwhile, based on the beta esterase activity test, most of the mosquitoes were moderate resistance. Conclusions: This study suggests that Aedes aegypti population from DHF endemic subdistrict in Riau, Indonesia are indicated to develop resistance to organophosphate.
Background: Cases of multidrug resistant tuberculosis (MDR TB) is increasing in number in the world and requires early detection to prevent further transmission. GeneXpert MTB/RIF is a tool that can be used for detection of rifampicin resistance, as a surrogate marker for MDR TB. This study aims to assess the sensitivity and specificity of the GeneXpert MTB/RIF in diagnosis of MDR TB. Methods: diagnostic test study was conducted at a poly MDR TB General Hospital Haji Adam Malik Medan. The subjects were all suspected MDR TB who had results positive GeneXpert MTB/ RIF with sensitive rifampin or resistant rifampin and had a drug sensitivity test results with the proportion method Lowenstein Jensen medium. Data retrieved from the medical records, between January until December 2013. Results: founded 64 samples that had results of GeneXpert MTB/RIF test positive and had the results of drug sensitivity, 87.5% of rifampin-resistant samples were also resistant to isoniazid. The GeneXpert MTB/RIF examination showed the sensitivity of 92.86% and the specificitu of 59.09%. Conclusion: GeneXpert MTB/ RIF has a high sensitivity for diagnosing MDR TB compared the gold standard drug sensitivity testing proportion method on Lowenstein Jensen medium. This study recommends the GeneXpert MTB/RIF be used for MDR TB screening tool. Keywords: GeneXpert MTB/RIF, multidrug resistant tuberculosis, drug susceptibility test, Lowenstein Jensen medium
Abstract. Dengue hemorrhagic fever (DHF) is a very serious health problem, especially in Indonesia. Dengue hemorrhagic fever is caused by the Dengue Virus transmitted by Aedes aegypti mosquito vector as the actual vector and Aedes albopictus as the potential vector. Various efforts have been implemented but the incidence of dengue is still high. One of the spearheads in eradicating DHF is to break the chain of transmission through the Mosquito Nest Eradication program. To support the PSN program, Jumantik Monitors are formed in each village. However, due to limited resources, monitoring by jumantik has not been entirely successful. Based on this, it is necessary to consider the effectiveness of the implementation of this jumantik through the SARUJU program, namely the one jumantik per house program. Jumantik was a medical student at the University of Riau who became a foster child in village namely Pelita Medika Buluh Cina Village. Jumantik has the duty to monitor the existence and density of larvae, implement PSN and appoint a second jumantik who is a member of the original family. Through the first stage larvae survey, there was a high rate of larvae density. Through Saruju activities, it is expected that a decrease in larvae density will reduce the incidence of DHF. Keywords: Dengue hemorrhagic fever, Saruju, JumantikAbstrak. Demam berdarah dengue (DBD) merupakan masalah kesehatan yang sangat serius, terutama di Indonesia. Demam berdarah dengue disebabkan oleh Virus Dengue dengan perantaraan vektor nyamuk Aedes aegypti sebagai vektor aktual dan Aedes albopictus sebagai vektor potensial. Berbagai upaya telah dilakukan pemerintah melalui program yang telah dilaksanakan, namum kejadian DBD masih tetap tinggi. Salah satu ujung tombak pemberantasan DBD adalah dengan memutus rantai penularan melalui program Pemberantasan Sarang Nyamuk (PSN). Namun demikian program tersebut tidak dilaksanakan secara efektif pada berbagai lapisan masyarakat. Untuk menunjang program PSN dibentuklah Juru Pemantau Jentik (Jumantik) pada tiap kelurahan. Namun demikian karena keterbatasan sumber daya menyebabkan pemantauan oleh jumantik tidak berhasil Berdasarkan hal tersebut perlu dipikirkan efektifitas pelaksanaan jumantik ini melalui gerakan SARUJU yaitu gerakan satu rumah satu jumantik. Jumantik berasal dari mahasiswa Fakultas Kedokteran UNRI yang merupakan anak asuh dari Desa Binaan Kampung Pelita Medika II Buluh Cina. Jumantik berkewajiban memantau keberadaan dan kepadatan jentik di rumahnya, melaksanakan PSN, serta menunjuk dan mengedukasi jumantik kedua yang merupakan anggota keluarga asli. Berdasarkan survey jentik didapatkan kepadatan jentik yang tinggi di daerah tersebut. Melalui kegiatan saruju diharapkan kejadian DBD di daerah tersebut dapat ditekan.Kata kunci: Demam berdarah dengue, Saruju, Jumantik
<p>Excessive usage of synthetic pediculicides, such as permethrin, lindane, and malathion, can induce resistance, environmental pollution, health problems, and even death. Efforts to prevent the side-effects of synthetic pediculicides are needed, one of which is by shifting to powerful yet safe natural pediculicides, such as Citrus limon (lemon) and Allium sativum (garlic). This study aimed to observe the effective concentration of Citrus limon and Allium sativum in vitro on the mortality of Pediculus humanus capitis (P. h. capitis). This research was an experimental laboratory study conducted in July to September 2019 in the Laboratory of Parasitology at Faculty of Medicine, University of Riau, while the making of Allium sativum extract was done at the Faculty of Mathematics and Science, University of Riau. A total of 288 samples of adult P. h. capitis was taken from children in two orphanages in Pekanbaru. Citrus limon juice and Allium sativum extract of 25%, 50%, 75%, and 100% concentrations, permethrin 1% as the positive control, and distilled water as the negative control were used in this study, and repetition was done three times. P. h. capitis mortality was observed every 10 - 120 minutes, characterized by the absence of movement of the legs and antenna. Data analysis was performed after 120 minutes with the one-way ANOVA test, LSD (=0.05), and Lethal Concentration 50 test (LC50). The one-way ANOVA test results of this study showed that statistically Citrus limon juice and Allium sativum extracts showed differences in each treatment formulation of juice on P. h. capitis mortality (Sig 0.017<0.05 and Sig 0.000<0.05) and LC50 juice of Citrus limon and Allium sativum extract by 51.999% and 72.426%. In this study, Citrus limon juice and Allium sativum extract had effect as pediculicides.</p>
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