We present the first documented case of Trypanosoma cruzi-induced orchitis in a rhesus macaque. Additionally, we describe an in situ hybridization-based assay to confirm T. cruzi infection in formalin-fixed tissues.

Cutaneous epitheliotropic lymphoma (CEL) is a rare neoplasm of T-cell lymphocytes with a tropism for epidermis and adnexal components. 1-4 CEL, or epidermotropic lymphoma, 5,6 was first reported in humans as a condition called mycosis fungoides (MF). 7 CEL is extremely rare in non-canid species 4 ; there have been no reports of CEL in non-human primates (NHPs). We present a case of CEL in a 9-year-old baboon and present a brief review of CEL in veterinary literature. | C A S E REP ORTThe 9-year-old female baboon (Papio spp.) was maintained at the Southwest National Primate Research Center and presented with raised pruritic lesions on the right forearm skin. The animal was treated with cephalexin (538.5 mg, PO BID, Lupin Pharmaceuticals) for 1 week. The lesion persisted, and following the results of a skin punch biopsy, the animal was euthanized 2 months later. All animal care and procedures were approved by the Texas Biomedical Research Institute Institutional Animal Care and Use Committee.A complete necropsy was performed; except for the skin and axillary lymph node (enlarged), the rest of the organs were AbstractCutaneous epitheliotropic lymphoma (CEL) has not been reported in non-human primates. We report the first case of CEL in a 9-year-old baboon. The phenotype of the neoplastic cells in this baboon is similar to CEL in humans (CD3+, CD4+, CD8−) and different from dogs (CD3+, CD4−, CD8+).

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