Background: Hepatitis C virus (HCV) infection is a global health problem and a major cause of morbidity and mortality. The current study aimed to assess the correlation between the patients with the hepatitis C virus and their health-related quality of life. Descriptive design was used. Setting: Carried out at liver virology outpatient. Subject: A convenient sample of two hundred adult patients with HCV newly received Sofosbuvir and Daclatasvir. Tools: Interview questioner and medical data sheet and Short-Form health survey (SF-36) questionnaire. Results: An improvement in the total quality of life this appear through 51.0% of hepatitis patients were poor in quality of life before treatment with Sofosbuvir and Daclatasvir medication while (62.0%) of them become excellent in quality of life after 3 months from treatment with highly statistically significant differences. Also, there was a fair negative association between the duration of disease of the studied patients with their total quality of life measured by shortform of health before administration of treatment with Sofosbuvir and Daclatasvir. Conclusion: The study concluded that the administration of Sofosbuvir and Daclatasvir for patients had positive effect on their quality of life especially for newly diagnosed patients. Recommendation: The study recommended that early screening for hepatitis C to begin early suitable treatment.

Background: Diabetes is a serious chronic disease. Uncontrolled diabetes and poor diabetic patients' knowledge can lead to a high morbidity and mortality. The aim of this study was to assess the effectiveness of structured teaching program on improvement of diabetic patient's health information, treatment adherence and glycemic control. Method: A quasi-experimental research design (pre posttest) was utilized on 72 diabetic patients at Minia University and general hospitals. A Structured Interview questionnaire about diabetic knowledge and treatment adherence. Glucose monitoring parameter (Glycated Hemoglobin & Random Blood Sugar),was monitored. Results: There was a highly a significant improvement in diabetic patients knowledge, treatment adherence and glycemic control post 1 st and 2 nd follow than pre application of teaching program. Conclusion: The diabetic teaching program would improve patient's knowledge about disease, treatment adherence and glycemic control. Recommendations: Nurses should emphasis to provide an teaching program tailored to each diabetic patient and increase their awareness about the importance of diabetic education to improve glycemic control.

Background: One of the difficulties faced by surgical patients is pain; 60% of them report postoperative anxiety and mild to moderate discomfort. Acupressure is a complementary and alternative medicine therapy that promotes relaxation and pain relief. Aim: This study aimed to examine the efficacy of acupressure on post-operative pain, anxiety level, and sleep quality in abdominal surgical patients. Study Design: A quasi-experimental study design was utilized to meet the aim of the study. Setting: The study was conducted in the surgical unit, and outpatients at Minia University Hospital. Subjects: 80 patients were split evenly between the control and acupressure groups, with 40 patients in each. Tools: Four tools were used: a structured interviewing questionnaire, a numerical scale of pain, the state trait anxiety inventory, and the Arabic Pittsburgh Sleep Quality Index. Results: There was no significant difference in score of pain, anxiety and sleep quality before intervention among both groups, but post acupressure intervention the score in the Acupressure group was significant reduced pain, anxiety and sleep quality scores compared to control group (p<0.001). Conclusion: Acupressure is a useful intervention for easing pain, calming anxiety, and enhancing sleep quality. Recommendations: The study recommended training nurses to use acupressure as a useful method for controlling pain and anxiety and enhancing sleep quality.

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Background: Despite the growing demand for blood and its products, some people, particularly the youth, are reluctant to donate blood. Aim: To evaluate the effect of the orientation program on undergraduate nursing students' performance regarding blood donation. Subjects and method: Design: A quasi-experimental research design was used to achieve the aim of this study. Setting:The study was conducted at the Faculty of Nursing, Minia University, Egypt on the undergraduate nursing students. Subjects: The sample consisted of convenient 900 undergraduate nursing students selected from the previous setting. Tool: A self-administered related questionnaire was designed using an electronic survey (Google form) which included four parts: Part I: undergraduate nursing students' demographic characteristics, Part 2: undergraduate nursing students' knowledge regarding blood donation, Part 3: undergraduate nursing students' attitudes regarding blood donation, Part 4: undergraduate nursing students' practices regarding blood donation. The link to the survey was sent to the respondents via WhatsApp groups. Results: The study result revealed that more than onethird of studied undergraduate nursing students had a poor level of knowledge, and more than half of them had an inadequate level of practice about blood donation before the implementation of the program. The majority of students had a good level of knowledge and most of them had a satisfactory level of practice after implementing the program. There was a highly statistically significant difference and improvement in undergraduate nursing students' knowledge, attitude, and practice after program implementation than pre-implementation. Conclusion: The findings of the study concluded that orientation program had positive effects on improving undergraduate nursing students' performance regarding blood donation. Recommendations: The study recommended organized blood donation orientation program are required to increase undergraduate nursing students' knowledge, attitudes, and practices toward blood donations.