Adrenal myelolipoma is a rare benign tumor, and contrary to most of the adrenal tumors it is an endocrinologically inactive tumor. Mature adipose tissue, and active bone marrow components identified during histopathological examination are diagnostic clues. They are generally small in size, and detected incidentally. Its definitive etiology has not been determined yet. However multiple number of etiopathogenetic factors have been defined. Hematopoietic stem cell embolization in the adrenal gland is one of the most probable theories. In this case report we present a 31-year-old patient whose pregnancy was terminated 10 months previously who developed rapidly progressive giant adrenal myelolipoma during the course of her pregnancy. According to literature findings, our case presented in the study is the first case who presented with abdominal pain during postpartum period. We think that this progressively increasing mass during nearly 10 months might be related to pregnancy.