Inner ear involvement may occur in systemic autoimmune diseases. Although there are studies evaluating hearing in psoriasis patients, its effect on the balance system is not clear. The aim of the present study was to evaluate the audiovestibular system in psoriasis patients without joint involvement. In this prospective study, the audiovestibular system of 32 psoriasis patients without joint involvement and 35 healthy volunteers were evaluated. The severity of the disease was determined by the psoriasis area severity index (PASI). There was no significant difference between the groups in terms of hearing test results, while the abnormal caloric test response was significantly higher in the psoriatic patients. PASI scores of psoriasis patients with abnormal caloric test results were higher than those with normal caloric test response. In psoriasis patients without joint involvement, the hearing was not affected, but the vestibular system was. The severity of the disease was associated with vestibular involvement. Particularly in patients with severe psoriasis, it must be considered that the vestibular system might be affected, and vestibular evaluations should be performed.
Alopecia areata (AA) is an autoimmune disease that results in hair loss because of immune-mediated damage to the hair follicles.Other autoimmune diseases such as autoimmune thyroiditis, psoriasis, vitiligo, systemic lupus erythematosus and pernicious anaemia may accompany AA. It has been reported that the inner ear may be affected in these systemic autoimmune diseases, including AA. [1][2][3][4][5][6] It has been reported that follicular melanocytes are an important target for autoimmunity in AA patients. 7,8 Bulb melanocytes are essential for the follicular cycle and loss of melanocytes can result in hair loss. However, it is not clear whether melanocytes are primarily affected in the pathogenesis of AA or affected secondarily because of autoimmune damage in the hair follicle. Apart from the hair bulb, melanocytes are also found in the epidermis, the uveal tract and retinal pigment epithelium in the eye, the inner ear and the leptomeninges. 2 Just as melanocytes in the hair bulb play an important role in the follicular cycle, melanocytes in the inner ear are also
In the present study we found that exposure to noise can cause vestibular dysfunction. And the vHIT is easily applicable, quick and practical and can individually evaluate all semicircular channels. Therefore, to evaluate vestibular function with vHIT is quick and practical.
Vitiligo is a systemic disease that affects not only the skin but also other areas that contain melanocytes, such as the inner ear. Studies of the effect of vitiligo on hearing loss have shown inconsistent results, and it is not clear which parameters related to the disease affect hearing. The aim of this study was to determine which disease‐related parameters trigger damage to cochlear melanocytes in vitiligo patients and the effect of vitiligo on the outer hair cells and hearing. Thirty‐one vitiligo patients and 40 sex‐ and age‐matched healthy volunteers were evaluated. The conventional pure tone audiometry (C‐PTA) test and the distortion product otoacoustic emission (DPOAE) test were performed. There was no significant difference between vitiligo patients and controls in C‐PTA test results, but the DPOAE test results were abnormal in vitiligo patients. The duration of the disease was significantly related to hypoacusis. As the duration of the disease increases, cochlear dysfunction may increase. Especially in patients with longer disease duration, otoacoustic emission tests should be performed in addition to conventional audiometry tests for early detection of damage to the outer hair cells.
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