This study aimed to describe the perceived stress levels and coping mechanisms related to COVID-19, and whether coping is related to well-being in people with self-reported chronic conditions and disabilities. Research Method/Design: A cross-sectional survey design was implemented. The total number of participants were 269 individuals with self-reported disabilities and chronic conditions (M age ϭ 39.37, SD age ϭ 12.18). We examined the relationship between perceived stress and coping strategies related to COVID-19, and which COVID-19 coping strategies were associated with well-being after controlling for demographic and psychological characteristics. Results: Correlation analyses demonstrated that perceived stress related to COVID-19 was positively associated with coping strategies including self-distraction, denial, substance use, behavioral disengagement, venting, planning, religion, and self-blame. Further, hierarchical regression results demonstrated that active coping, denial, use of emotional support, humor, religion, and self-blame were associated with participants' well-being after controlling for demographic and psychological characteristics. Conclusions/Implications: This exploratory study findings suggest that measuring and quantifying COVID-19 related stress and coping strategies in individuals with chronic conditions and disabilities can help clinicians and researchers understand potential effects of COVID-19 among people with chronic conditions and disabilities. Impact and ImplicationsThe current exploratory study extends the literature by exploring the perceived impact of COVID-19, stress levels and coping mechanisms related to COVID-19, and which coping strategies are associated with well-being in individuals with self-reported chronic conditions and disabilities. Active coping, denial, use of emotional support, humor, and religion coping were found to be positively correlated with well-being scores. Self-blame was found to be negatively correlated with well-being scores.

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These analyses provide preliminary support for IICV as a marker of incident AD and MCI. This easily-disseminated, non-invasive marker compared favorably to well-established CSF biomarkers.

The clearest career path to the middle class generally involves access, and completion, of postsecondary education. For youth with disabilities, the knowledge and skills obtained through a college can limit the impact of a disability on obtaining high-quality employment. However, persons with disabilities are less likely to enroll in postsecondary education programs or graduate from those programs compared with their same-age peers without disabilities (Stodden, Stodden, Kim-Rupnow, Thai Nghi, & Galloway, 2003; Stodden, Whelley, Chang, & Harding, 2001). The lower attendance and higher attrition rates of youth with disabilities may be due to less effective study habits, study skills, and test-taking strategies than students without dis

IntroductionThe potential of intra-individual cognitive variability (IICV) to predict incident mild cognitive impairment (MCI) or Alzheimer's disease (AD) was examined and compared to well-established neuroimaging and genetic predictors.MethodsIICV was estimated using four neuropsychological measures for n = 1324 Alzheimer's Disease Neuroimaging Initiative (ADNI) participants who were cognitively healthy or diagnosed with MCI at baseline. IICV was used to predict time to incident MCI or AD, and compared to hippocampal volume loss and APOE ε4 status via survival analysis.ResultsIn survival analyses, controlling for age, education, baseline diagonosis, and APOE ε4 status, likelihood ratio tests indicate that IICV is associated with time to cognitive status change in the full sample (P < .0001), and when the sample was restricted to individuals with MCI at baseline (P < .0001).DiscussionThese findings suggest IICV may be a low-cost, noninvasive alternative to traditional AD biomarkers.