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The aim of this work was to analyze the effect of fibrin biopolymer sealant (FS) associated or not to aquatic exercise (AE) on the calcaneal tendon repair. Methods: Forty-four female Wistar rats were randomly divided into four experimental groups: Lesion control (L), Lesion and FS (LS), Lesion and AE (LE) and Lesion and FS associated to AE (LSE). The edema volume (EV), collagen ratio, and histopathological analysis were evaluated after 7, 14, and 21 days of partial tendon transection. Results: The EV was statistically reduced for all treatment groups after 7 and 21 days when compared to L group. The LS and LSE had the highest EV reduction after 21 days of treatment. The FS group didn't induce tissue necrosis or infections on the histopathological analysis. It was observed tenocytes proliferation, granulation tissue and collagen formation in the tendon partial transection area in the FS group. The LSE demonstrated higher amount of granulation tissue and increased the collagen deposition at the injury site. Conclusions: Our data suggests that the therapeutic potential of the association of heterologous fibrin biopolymer sealant with aquatic exercise program should be further explored as it may stimulate the regeneration phase and optimize calcaneal tendon recovery.

In the face of controversies about the treatment of tendon injuries, non-surgical treatment using photobiomodulation therapy has been shown to be effective in repair. Objective was to evaluate the effects of photobiomodulation therapy on the tendon repair process. 42 Rattus norvegicus belonging to the wistar lineage were used, which were randomly divided into 2 experimental groups: Control (CG); Photobiomodulation (PBM). The groups were subdivided into 3 experimental periods: 7, 14 and 21 days. PBM started 24 hours after injury induction and followed for 7, 14, 21 days. For FBM, the 660 nm, 40 mW, 0.23 J and 6 s laser was used. The volume of the edema was evaluated, immediately before the tendon transection; 24 hours later; on the day of euthanasia, following their respective experimental periods. Histopathological analysis of the region of the transect and the quantification of blood vessels were performed using HE. Edema results: 24 hours after injury induction, there was no statistical difference between the experimental groups. After the experimental periods, 7, 14 and 21 days, the PBM group was effective in reducing the edema compared to the control. Histological results revealed that the PBM group had a greater tendon injury compared to the control after 7 days. After 14 and 21 days, the PBM group showed a better repair process compared to the control group. Likewise, PBM showed a greater number of blood vessels when compared to the control, after all experimental periods. The PBM treatment was effective in reducing the volume of the edema, preventing degenerative morphological alterations of the tendon, after 21 days.

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