Cutaneous manifestations such as chilblain-like acral eruptions, purpuric or erythema multiform-like lesions, acro-ischemic lesions, maculopapular rash, urticaria, and androgenetic alopecia (AGA) pattern hair loss were reported during COVID-19 disease. 1 Androgenetic alopecia during COVID-19 based on a hypothesis that includes a common pathway with SARS-CoV-2 replication in human cells and transcription promoters for androgens. 2 SARS-CoV-2 viral spike proteins undergo proteolytic priming by the transmembrane protease serine 2 (TMPRSS2) during entering the type II pneumocytes in the human. Androgens are the only known transcription promoters for the TMPRSS2 gene. 3 In addition, milder disease severity in prepubertal children and adult women has been associated with a low androgen receptor transcription in the literature. 3 Also, the correlation between AGA severity and COVID-19 severity has been observed earlier in the pandemic. 4,5 Rapidly progressive form of alopecia areata has been reported during COVID-19 infection. 6
Narrowband ultraviolet B (NB-UVB) phototherapy (311 nm) has become a widely used, standard treatment modality in dermatology since it was first introduced in the Netherlands in the early 1980s. 1-3 It is highly effective for the treatment of psoriasis, vitiligo, atopic dermatitis, lichen planus, and many other inflammatory skin diseases. 4,5
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