Defects in the corneal stroma caused by trauma or diseases such as macular corneal dystrophy and keratoconus can be detrimental for vision. Development of therapeutic methods to enhance corneal regeneration is essential for treatment of these defects. This paper describes a bioactive peptide nanofiber scaffold system for corneal tissue regeneration. These nanofibers are formed by self-assembling peptide amphiphile molecules containing laminin and fibronectin inspired sequences. Human corneal keratocyte cells cultured on laminin-mimetic peptide nanofibers retained their characteristic morphology, and their proliferation was enhanced compared with cells cultured on fibronectin-mimetic nanofibers. When these nanofibers were used for damaged rabbit corneas, laminin-mimetic peptide nanofibers increased keratocyte migration and supported stroma regeneration. These results suggest that laminin-mimetic peptide nanofibers provide a promising injectable, synthetic scaffold system for cornea stroma regeneration.

This study suggests that oxidative stress may be an important factor on expression of miRNAs in ARPE-19 cells. These miRNAs may have a role in the pathogenesis of age-related macular degeneration related to oxidative stress. However, this relationship needs to be examined in new studies by evaluation of pathways and target genes.

Influenza vaccine is effective in reducing AOM and OME episodes in 6- to 60-month-old day care children, especially during influenza season.

CAPE has a protective effect on ARPE-19 cells against oxidative stress, and VEGF protein level and expression can be decreased by incubation with different concentrations of CAPE. These results demonstrate that CAPE suppresses the mitochondria-mediated apoptosis in ARPE-19 cells under oxidative stress. In addition, the use of CAPE in combination with bevacizumab has an additive effect.

A 42-year-old woman was admitted to Mersin University, Department of Ophthalmology Clinic with itching and burning sensation of the right eye for 3 weeks. In her slit-lamp examination, nits and lice, attached to the upper and lower eyelashes of her right eye, were observed. Lice and nits were destroyed by argon laser phototherapy and were removed with the help of a fine forceps thereafter. Argon laser phototherapy is a quick, effective, and safe treatment modality for phthiriasis palpebrarum. ÖZKırk iki yaşındaki bayan hasta sağ gözünde 3 haftadır devam eden kaşıntı ve yanma şikayeti ile kliniğimize başvurdu. Biomikroskopik muayenede sağ gözde alt ve üst kapakta kirpiklere sıkıca yapışık olan sirkelerin ve bitlerin olduğu izlendi. Bitler ve sirkeler argon lazer ile öldürüldü ve forseps yardımıyla uzaklaştırıldı. Argon lazer fototerapi phthiriasis palpebrarum tedavisinde hızlı, etkin ve güvenilir tedavi yöntemlerinden birisidir. (Turkiye Parazitol Derg 2015; 39: 252-4)