has caused a pandemic crisis that threatens the world in many areas, especially in public health. For the diagnosis of COVID-19, computed tomography has a prognostic role in the early diagnosis of COVID-19 as it provides both rapid and accurate results. This is crucial to assist clinicians in making decisions for rapid isolation and appropriate patient treatment. Therefore, many researchers have shown that the accuracy of COVID-19 patient detection from chest CT images using various deep learning systems is extremely optimistic. Deep learning networks such as convolutional neural networks (CNNs) require substantial training data. One of the biggest problems for researchers is accessing a significant amount of training data. In this work, we combine methods such as segmentation, data augmentation and generative adversarial network (GAN) to increase the effectiveness of deep learning models. We propose a method that generates synthetic chest CT images using the GAN method from a limited number of CT images. We test the performance of experiments (with and without GAN) on internal and external dataset. When the CNN is trained on real images and synthetic images, a slight increase in accuracy and other results are observed in the internal dataset, but between 3% and 9% in the external dataset. It is promising according to the performance results that the proposed method will accelerate the detection of COVID-19 and lead to more robust systems.
Diagnose the infected patient as soon as possible in the coronavirus 2019 (COVID-19) outbreak which is declared as a pandemic by the world health organization (WHO) is extremely important. Experts recommend CT imaging as a diagnostic tool because of the weak points of the nucleic acid amplification test (NAAT). In this study, the detection of COVID-19 from CT images, which give the most accurate response in a short time, was investigated in the classical computer and firstly in quantum computers. Using the quantum transfer learning method, we experimentally perform COVID-19 detection in different quantum real processors (IBMQx2, IBMQ-London and IBMQ-Rome) of IBM, as well as in different simulators (Pennylane, Qiskit-Aer and Cirq). By using a small number of data sets such as 126 COVID-19 and 100 Normal CT images, we obtained a positive or negative classification of COVID-19 with 90% success in classical computers, while we achieved a high success rate of 94-100% in quantum computers. Also, according to the results obtained, machine learning process in classical computers requiring more processors and time than quantum computers can be realized in a very short time with a very small quantum processor such as 4 qubits in quantum computers. If the size of the data set is small; Due to the superior properties of quantum, it is seen that according to the classification of COVID-19 and Normal, in terms of machine learning, quantum computers seem to outperform traditional computers.
Computerized Tomography (CT )has a prognostic role in the early diagnosis of COVID-19 due to it gives both fast and accurate results. This is very important to help decision making of clinicians for quick isolation and appropriate patient treatment. In this study, we combine methods such as segmentation, data augmentation and the generative adversarial network (GAN) to improve the effectiveness of learning models. We obtain the best performance with 99% accuracy for lung segmentation. Using the above improvements we get the highest rates in terms of accuracy (99.8%), precision (99.8%), recall (99.8%), f1-score (99.8%) and roc acu (99.9979%) with deep learning methods in this paper. Also we compare popular deep learning-based frameworks such as VGG16, VGG19, Xception, ResNet50, ResNet50V2, DenseNet121, DenseNet169, InceptionV3 and InceptionResNetV2 for automatic COVID-19 classification. The DenseNet169 amongst deep convolutional neural networks achieves the best performance with 99.8% accuracy. The second-best learner is InceptionResNetV2 with accuracy of 99.65\%. The third-best learner is Xception and InceptionV3 with accuracy of 99.60%.
Diagnose the infected patient as soon as possible in the coronavirus 2019 (COVID-19) outbreak which is declared as a pandemic by the world health organization (WHO) is extremely important. Experts recommend CT imaging as a diagnostic tool because of the weak points of the nucleic acid amplification test (NAAT). In this study, the detection of COVID-19 from CT images, which give the most accurate response in a short time, was investigated in the classical computer and firstly in quantum computers. Using the quantum transfer learning method, we experimentally perform COVID-19 detection in different quantum real processors (IBMQx2, IBMQ-London and IBMQ-Rome) of IBM, as well as in different simulators (Pennylane, Qiskit-Aer and Cirq). By using a small number of data sets such as 126 COVID-19 and 100 Normal CT images, we obtained a positive or negative classification of COVID-19 with 90% success in classical computers, while we achieved a high success rate of 94-100% in quantum computers. Also, according to the results obtained, machine learning process in classical computers requiring more processors and time than quantum computers can be realized in a very short time with a very small quantum processor such as 4 qubits in quantum computers. If the size of the data set is small; Due to the superior properties of quantum, it is seen that according to the classification of COVID-19 and Normal, in terms of machine learning, quantum computers seem to outperform traditional computers.
The new coronavirus (COVID-19) appeared in Wuhan in December 2019 and has been announced as a pandemic by the World Health Organization (WHO). Currently, this deadly pandemic has caused more than 1 million deaths worldwide. Therefore, it is essential to detect positive cases as early as possible to prevent the further spread of this outbreak. Currently, the most widely used COVID-19 detection technique is a real-time reverse transcription-polymerase chain reaction (RT-PCR). However, RT-PCR is time-consuming to confirm infection in the patient. Because RT-PCR is less sensitive, it provides high false-negative results. Computed tomography (CT) is recommended as a solution to this problem by healthcare professionals because of its higher sensitivity for early and rapid diagnosis. In addition, radiation used in CT poses a serious threat to patients. In this study, we propose a CNN-based method to distinguish COVID-19 pneumonia from other types of viral and bacterial pneumonia using low-dose CT images to reduce the radiation dose used in CT. In our study, we used a data set consisting of 7717 CT images of 350 patients that we collected from Çanakkale Onsekiz Mart University Research Hospital. We used a CNN-based network that suppresses noise to remove interference from low-dose CT images. In the image preprocessing phase, we provided lung segmentation from CT images and applied quantum Fourier transform. By evaluating all possible variations of local knowledge at the same time with quantum Fourier transformation, the most informative spatial information was extracted. In CNN-based architecture, we used pre-trained ResNet50v2 as a feature extractor and fine-tune by training with our dataset. We visualized the efficiency of the ResNet50v2 network using the t-SNE method. We performed the classification process with a fully connected layer. We created a heat map using the GradCam technique to see where the model focuses on the images while classifying. In this experimental study, the results of 99.5%, 99.2%, 99.0%, 99.7%, and 99.1%, were obtained in the context of performance criteria such as accuracy, precision, sensitivity, specificity, and f1 score, respectively. This study revealed the artificial intelligence-based computer-aided diagnosis (CAD)system as an effective and fast method to accurately diagnose COVID-19 pneumonia.
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