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Background: Pulmonary arteriovenous malformations have been associated with clinical situations that put life at risk or cause physical disability. When the clinical picture is evident, percutaneous occlusion is recommended. Methods: We describe the use of an Amplatzer vascular plug in a female patient for the treatment of an idiopathic pulmonary arteriovenous malformation associated with syncope and transient ischemic attacks. Results: The patient was successfully treated via percutaneous intervention without complications. At 6 months followup, there was an absence of the pulmonary arteriovenous malformation confirmed via angiotomography and a full reintegration into her daily activities with no-clinical eventualities. Conclusion: The use of an Amplatzer vascular plug should be considered for the treatment of idiopathic pulmonary arteriovenous malformation. In experienced centers the procedure can be done safely with excellent clinical outcomes.

We report the case of 23-year-old man with mitral valve regurgitation and Glanzmann thrombasthenia, who underwent mechanical mitral valve replacement. Warfarin therapy was devastating, causing bilateral hemothorax, pericardial effusion, gastrointestinal bleeding, and hematuria. Redo mitral valve replacement with a biological prosthesis was required to resolve this critical situation. To our knowledge, this is the first report of mitral valve replacement in Glanzmann thrombasthenia, highlighting the danger of oral anticoagulation in this pathology.

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