BackgroundBreast cancer is the most common cancer among women and it affects quality of life of those women. So far, the two most frequently used tools for assessing health related quality of life in breast cancer patients, EORTC QLQ-C30 and EORTC QLQ-BR23 modules, were not validated in Ethiopia. Hence, the present study aimed to assess the psychometric properties of the tools among Ethiopian breast cancer patients.MethodsInstitutional based longitudinal study was conducted from January 1 to May 1, 2017 GC at only nationwide oncology center, Tikur Anbessa Specialized Hospital (TASH), Addis Ababa, Ethiopia. A total of 146 patients who visited the facility during that period, with no missing quality of life data, were selected for analysis. The psychometric properties of the EORTC QLQ-C30 and EORTC QLQ-BR23 were evaluated in terms of reliability, convergent, divergent, construct and clinical validity using SPSS version 22.ResultsSatisfactory internal consistency reliability (Cronbach’s α coefficients > 0.7) was confirmed, except for cognitive function (α = 0.516) of EORTC QLQ-C30 and body image (α = 0.510) of EORTC QLQ-BR23. Multiple-trait scaling analysis demonstrated a good convergent and divergent validity. No scaling errors were observed. Most items in EORTC QLQ-BR23 possessed a weak or no correlation with its own dimension in EORTC QLQ-C30 (r < 0.4) except with some of symptom scales. A statistically significant chemotherapy induced quality of life scores changes (P ≤ 0.05) were observed in all dimensions of both instruments between baseline and the end of first cycle chemotherapy, except for body image (P = 0.985) and sexual enjoyment (P = 0.817) of EORTC QLQ-BR23, indicating clinical validity.ConclusionAmharic version of the EORTC QLQ-C30 and EORTC QLQ-BR23 modules are valid and adequately reliable tool and can be used for clinical and epidemiological cancer researches to study the health related quality of life (HRQoL) of women with breast cancer in Ethiopia.

BackgroundMedicines wastage is one of the challenges of health supply chain management in developing countries including Ethiopia. However, there is lack of objective evidence on the detailed underlying causes of medicines wastage. Therefore, the aim of this study is to explore factors contributing for medicines wastage in selected public health facilities of South West Shoa Zone, Oromia Regional State, Ethiopia.MethodsA qualitative study was conducted in 10 public health facilities (1 General hospital and 9 health centers). An in-depth interview with flexible probing techniques was employed to collect the data from 20 key informants from May 2, 2016 to May 27, 2016. A semi structured interview guide was prepared to explore key informants’ idea about current situation of contributing factors and efforts made to reduce medicines wastage in public health facilities. A thematic analysis was then used to analyze the data.ResultsAlmost all key informants felt that medicines wastage is increasing from time to time in their health facility due to supplier’s issuing of medicines without health facilities’ needs and request, failure to follow first expired first out principle in issuing medicines from stores to different dispensing units, lack of communication between supplier and health facilities, inadequate number of pharmacy personnel and weak monitoring system of supply chain in the health facilities. They also revealed budget constraint, stock out of medicines and congested store are of the major challenge that are compromising their service provision.ConclusionMedicine wastage is an ever-increasing problem in public health facilities of South West Shoa Zone. The problem is exacerbated due to absence of mechanisms to minimize the wastage. Health facilities, therefore, should place a mechanism to exchange medicines from overstocked facilities to under stocked ones; has to improve store management capacity by employing competent professionals, equipping the store with necessary technology and introducing a monitoring and evaluating health supply chain performance system in the health facilities.

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Background One of the problems facing higher education institutions in developing countries such as Ethiopia is the poor quality of undergraduate students’ academic work. However, there is a scarcity of empirical data on the specific causes of the poor quality of undergraduate study. Therefore, the aim of this research is to explore factors that influence the quality of undergraduate pharmacy students’ research projects at Ambo University in Ethiopia, from the perspective of research advisors. Methods A qualitative study was held in Ambo University, Department of Pharmacy from March 2 to March 27, 2020. A total number of 15 research advisors were the participants of the study. A semi-structured interview questionaire was prepared to explore participants’ ideas about the current situation of research quality, underlying causes and perception towards outcomes of poor quality of undergraduate pharmacy students’ research projects. The necessary data were collected through in-depth interview and qualitative content analysis was employed to analyze the data. Results The majority of the key informants thought that the quality of undergraduate pharmacy students research projects is decreasing from time to time in their university due to students’ research knowledge gap, poor commitment, and motivation, lack of communication between students and advisors, plagiarism, financial problems, shortage of experienced research advisors, advisors less motivation and dedication, insufficient research facilities, lack of research fund, poor management support, and limitation of the undergraduate curriculum. They also revealed weak students’ research capacity, absence of knowledge transfer through research publication and presentation, and inadequate baseline evidence for the policymakers are the potential outcomes of poor quality undergraduate pharmacy students’ research projects. Conclusion Undergraduate research quality is a persistent problem in the department of pharmacy of Ambo University. The problem is exacerbated due to multiple factors. As a result, the university should establish a framework for collaboration among students, advisors, and university research leaders; it should also boost students’ research capacity by hiring qualified researchers, equipping the research facility with appropriate technology, and instituting a system for monitoring and evaluating research project results.