Bu çal›flmada bir e¤itim hastanesinde verilen psikiyatri konsültasyon hizmetlerinin hasta-lar›n sosyodemografik özelliklerine, istem yapan kliniklere, isteme nedenlerine ve konulan psikiyatrik tan›lara göre da¤›l›m› incelenmifltir. Çal›flma grubunu Ocak-A¤ustos 2007 tarihleri ara-s›nda Ankara Atatürk E¤itim ve Araflt›rma Hastanesi'nde psikiyatri d›fl› kliniklerde yatarak ve ayaktan tedavi gören ve psikiyatri konsültasyonu istenen 545 hasta oluflturmufltur. En fazla konsültasyon istemi dahiliye ve nöroloji kliniklerince yap›lm›flt›r. En s›k konsültasyon isteme nedeni ise bir gerekçe göstermeksizin hastan›n psikiyatrik yönden de¤erlendirilmesi olarak bulunmufltur. Yap›lan psikiyatrik de¤erlendirme sonras›nda en s›k konulan tan›lar anksiyete ve depresif bozukluklar olmufltur. Çal›flmam›z›n sonucunda psikiyatri d›fl› klinikler-de de¤erlendirilen hastalar›n tan› ve tedavilerinin düzenlenmesinde psikiyatrik konsültasyonun önemini vurgulayan sonuçlar elde edilmifltir.

We suggest that serum G72 protein levels may represent a candidate biomarker for schizophrenia and have confirmed the results of the previous preliminary study. Additional studies with larger sample sizes and the inclusion of first episode schizophrenia patients are required to clarify the reliability and validity of serum G72 protein levels as a biomarker for schizophrenia.

Quality of life and depression in schizophrenia patients living in a nursing homeObjective: Nursing homes are seen as alternative housing for patients with schizophrenia. However, it has not yet been established how suitable this accommodation is for schizophrenia patients. First aim of this study is to assess the quality of life and depression level in schizophrenic patients and compare this data with that of patients living with their families. Second aim is to assess factors related to the quality of living and depression state in all participants of this study. Method: This is a cross-sectional study conducted with patients presenting to the Psychotic Disorders Policlinic of the Beyhekim Psychiatric Clinic of Konya Training and Research Hospital consecutively between December 2012 and May 2013 who had received a diagnosis of schizophrenia according to DSM IV-TR. All participants were administered a sociodemographic data form, Brief Psychiatric Rating Scale (BPRS), Positive and Negative Syndrome Scale (PANSS), Calgary Depression Scale for Schizophrenia (CDSS), and Quality of Life Scale for Schizophrenia Patients (QLSSP). Results: CDSS scores were found to be significantly increased in schizophrenic patients living in nursing homes. Their QLSSP scores, including interpersonal relations, occupational role, mental symptoms, personal belongings/activity scores, and total scores were statistically significantly low. A significant negative correlation was observed between negative symptom levels and occupational area, mental findings, and the personal belongings/activity areas of quality of life. Between positive symptom levels and quality of life, only scores in the occupational area showed a significant negative correlation. A significant negative correlation between CSDS and QLS was observed in all areas. Conclusion: Quality of life and depression need to be evaluated in all schizophrenia patients, as they are conditions that significantly affect treatment and prognosis. Keywords: Depression, quality of life, schizophrenia ÖZET Bakımevinde kalan şizofreni hastalarında yaşam kalitesi ve depresyonAmaç: Bakımevleri şizofreni hastaları için alternatif yaşam alanları olarak görülmektedir. Ancak bu tür yerlerin şizofreni hastaları için ne kadar uygun olduğu sorusu henüz cevaplandırılmamıştır. Bu çalışmanın birinci amacı bakımevlerinde yaşayan şizofreni hastalarının yaşam kalitesini ve depresyon düzeylerini değerlendirmek ve ailesiyle yaşayan hastalarla karşılaştırmaktı. İkinci amacı ise çalışmaya alınan tüm hastaların yaşam kalitesi ve depresyon durumlarıyla ilişkili faktörlerin değerlendirilmesiydi. Yöntem: Bu çalışma Aralık 2012-Mayıs 2013 tarihleri arasında Konya Eğitim ve Araştırma Hastanesi, Beyhekim Psikiyatri Kliniği, Psikotik Bozukluklar Polikliniğine ardışık olarak başvuran DSM-IV-TR'ye göre şizofreni tanısı alan hastaların katıldığı kesitsel bir çalışmadır. Tüm katılımcılara sosyodemografik veri formu, Kısa Psikiyatrik Değerlendirme Olçeği (KPDÖ), Pozitif ve Negatif Sendrom Ölçeği (PNSÖ), Calgary Şi...

BackgroundBrain-derived neurotrophic factor (BDNF) is a well-established neurotrophin that plays a role in the pathophysiology of numerous psychiatric disorders. Many studies have investigated the serum BDNF levels in patients with schizophrenia. However, there are restricted data in the literature that compare the serum BDNF levels in patients with deficit and nondeficit syndromes. In this study, we aimed to compare the serum BDNF levels between schizophrenic patients with deficit or nondeficit syndrome and healthy controls.MethodsAfter fulfilling the inclusion and exclusion criteria, 58 patients with schizophrenia and 36 healthy controls were included in the study. The patients were grouped as deficit syndrome (N=23) and nondeficit syndrome (N=35) according to the Schedule for the Deficit Syndrome. Three groups were compared in terms of the sociodemographic and clinical variants and serum BDNF levels.ResultsThe groups were similar in terms of age, sex, body mass index, and smoking status. The serum BDNF levels in patients with deficit syndrome were significantly lower than those in healthy controls. In contrast, the serum BDNF levels in patients with nondeficit syndrome were similar to those in healthy controls.ConclusionThis study suggests that decreased BDNF levels may play a role in the pathophysiology of schizophrenic patients with deficit syndrome. Nonetheless, additional studies using a larger patient sample size are needed to investigate the serum BDNF levels in schizophrenic patients with deficit syndrome.

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