We report a case of a 3 year-old boy with possible typhoid fever with recent travel to a typhoid endemic area who was primarily managed as a case of multisystem inflammatory syndrome in children (MIS-C). The patient was initially treated for tonsillitis after a 3 day history of persistent fever, sore throat, and constipation. The patient presented later when he deteriorated. Severe acute respiratory syndrome coronavirus (SARS-CoV-2) viral RNA was not detected but the antibodies were positive. The patient went on to develop mucosal, cardiac, and gastrointestinal manifestations and was subsequently treated with immunoglobulins and corticosteroids for MIS-C. Despite the rarity of MIS-C as a complication of COVID-19 infection, the endemic typhoid fever which is relatively more common was not ruled out. The patient additionally received antibiotics for a total of 5 weeks given his unremitting fever. Even during the COVID-19 pandemic, healthcare professionals should carry out timely testing to exclude more probable differential diagnoses, with area-specific common diseases given due diligence.

We describe a case of post-coronavirus disease 2019 (COVID-19) multisystem inflammatory syndrome in children (MIS-C). The 12-year-old child presented with appendicitis-like symptoms in the form of gradually worsening abdominal pain localizing over the right iliac fossa, fever, and vomiting. After an appendectomy, the abdominal pain did not resolve. He later developed orthopnea, bilateral lower limb pitting edema, and bilateral fine basal crepitations. This pointed to MIS-C. We should be mindful of multisystem inflammatory syndrome in children in children with a recent history of COVID-19.

We describe a complicated case of dextro-transposition of the great arteries (d-TGA) that was treated unusually late at age four by Glenn Shunt operation with pulmonary artery banding. She presented fteen years later with superior vena cava syndrome as a consequence of Glenn shunt failure and was managed conservatively. Glenn Shunt with pulmonary artery banding can be done for Dextro-TGA patients in which arterial switch operation is contraindicated; however, pulmonary artery banding failure can cause a functional obstruction leading to fatal SVC syndrome. Key points1. Glenn Shunt with pulmonary artery banding could be done for Dextro-TGA patients in which arterial switch operation is contraindicated 2. Glenn Shunt with pulmonary artery banding failure can cause a functional obstruction leading to fatal SVC syndrome