; Tel : +225 78 83 60 66 RESUME L'étude du pouvoir lactogène de Euphorbia hirta (Euphorbiaceae) et Secamone afzelii (Asclepiadaceae) a été menée sur des rates adultes non accouplées. En effet, les animaux ont reçu par voie orale, pour certains, les extraits aqueux des plantes et pour d'autres, le galactogil. Puis des observations ont été faites sur les mamelles. Les résultats ont montré une similitude dans le développement morphologique de l'aréole mammaire chez les rates traitées avec les extraits de plantes et le galactogil, contrairement aux rates témoins non traités. L'analyse phytochimique a montré que les deux plantes contiennent des stérols qui sont des molécules essentielles dans la biosynthèse de phytohormones. Cette étude met en évidence l'effet lactogène des deux plantes et justifie leur usage en médecine traditionnelle comme galactagogue. © 2017 International Formulae Group. All rights reserved.Mots clés: Plantes galactogènes, galactagogue, aréole mammaire, pouvoir lactogène, prolactine.Effect on breast development and phytochemical analysis of two lactogenic plants of the traditional ivorian pharmacopoeia: Euphorbia hirta L. and Secamone afzelii (Roem. &Schult.) ABSTRACTThe Study of the lactogenic ability of two plants such as Euphorbia hirta (Euphorbiaceae) and Secamone afzelli (Asclepiadaceae) implimented on non-mated adult rats. Indeed, some rats received orally aqueous extracts of both plants and others received the galactogil. Afterwards observations were done on the rats teats. Results showed a similarity with rats treated with both plants and those treated with galactogil which is the morphologic development of the mammary areola; unlike rats that didn't undergo treatment. Phytochemical analysis showed both plants contain sterols which are essential molecules in the biosynthesis of Y. P. ADEPO et al. / Int. J. Biol. Chem. Sci. 11(4): 1872-1877, 2017 1873 phytohormones. This study brings out the lactogenic effect of the two plants and justifies their use in folk medicine as galactogogue.
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