Background High-throughput sequencing generates large volumes of biological data that must be interpreted to make meaningful inference on the biological function. Problems arise due to the large number of characteristics p (dimensions) that describe each record [n] in the database. Feature selection using a subset of variables extracted from the large datasets is one of the approaches towards solving this problem. Methodology In this study we analyzed the transcriptome of Glossina morsitans morsitans (Tsetsefly) antennae after exposure to either a repellant (δ-nonalactone) or an attractant (ε-nonalactone). We identified 308 genes that were upregulated or downregulated due to exposure to a repellant (δ-nonalactone) or an attractant (ε-nonalactone) respectively. Weighted gene coexpression network analysis was used to cluster the genes into 12 modules and filter unconnected genes. Discretized and association rule mining was used to find association between genes thereby predicting the putative function of unannotated genes. Results and discussion Among the significantly expressed chemosensory genes (FDR < 0.05) in response to Ɛ-nonalactone were gustatory receptors (GrIA and Gr28b), ionotrophic receptors (Ir41a and Ir75a), odorant binding proteins (Obp99b, Obp99d, Obp59a and Obp28a) and the odorant receptor (Or67d). Several non-chemosensory genes with no assigned function in the NCBI database were co-expressed with the chemosensory genes. Exposure to a repellent (δ-nonalactone) did not show any significant change between the treatment and control samples. We generated a coexpression network with 276 edges and 130 nodes. Genes CAH3, Ahcy, Ir64a, Or67c, Ir8a and Or67a had node degree values above 11 and therefore could be regarded as the top hub genes in the network. Association rule mining showed a relation between various genes based on their appearance in the same itemsets as consequent and antecedent.
Biometric systems have been used extensively in the identification and verification of persons. Fingerprint biometrics stands out as the most effective due to their characteristics of Permanence, uniqueness, ergonomics, throughput, low cost, and lifelong usability. By reducing the number of comparisons, biometric recognition systems can effectively deal with large-scale databases. Fingerprint classification is an important task used to reduce the number of comparisons by dividing fingerprints into classes.Deep learning models have demonstrated impressive classification performance in fingerprint classification tasks. The high-level features of deep learning models can affect the transfer learning in deep learning models. Furthermore, the high-level features involve high computational costs that can render difficulty in the deployment of the applications. This work proposes an improved system for fingerprint classification through the truncation of layers and transfer learning. Our approach modifies the ResNet50 model to improve its network inference speed and performance in fingerprint classification by removing some deep convolutional layers. We then finetune the modified model and train it using a fingerprint dataset. The results show that the finetuned modified model improves classification accuracy at a reduced computational cost. At only 5.1M parameters, our model obtained a classification accuracy of 93.3% and precision of 93.4% performing better than previous studies based on its size-performance ratio.
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