The gold standard diagnosis of DHF by RT-PCR needs a complex technology and is time consuming. Serological tests have beendeveloped to detect IgM and IgG anti dengue to determine primary as well as secondary acute phase infection. IgM and IgG antidenguetests by immunochromatography have been used, due to a high diagnostic validity, also because they are simple, practicable, easy, rapid(15–30 minutes), can be used in a single serum sample. ELISA method has been used as a confirmation method. The aim of this studyis to evaluate the immunochromatography method in detecting IgG and IgM anti dengue of DHF patients. The study was performedon 50 serum samples from patients of the ICU Department of Paediatrics Dr. Soetomo Hospital, Surabaya during July–August 2005with dengue virus infection according to the 1997, WHO criterion and 27 serum samples from non dengue virus infection patients.ELISA method showed positive infection in 44 samples. Immunochromatography method showed positive infection in 43 samples, butwas negative in 1 sample. Diagnostic sensitivity of Immunochromatography is 97.7% (43/44) and the diagnostic specificity is 92.6%(25/27). Immunochromatography method has a high diagnostic value in assisting the diagnosis of DHF.

Diabetes mellitus (DM) is a chronic metabolic disease that characterized by elevated blood glucose levels. Warfarin is an anticoagulant drug that is often used to treat and prevent microvascular and macrovascular complications. This study wanted to find out the effect of warfarin on the tail bleeding time of male Wistar rats with type 2 diabetes mellitus model. This study used quasi-experimental with posttest research design with an in vivo control group with male Wistar rats model DMT2 induced by nicotinamide and streptozotocin, the experimental group was given warfarin at a dose of 2 mg/Kg of body weight. The number of samples as many as 24 tails. The samples were divided into 4 groups, namely DM + Warfarin, DM + Aquades, Normal + Warfarin, Normal + Aquades. Data were analyzed by Kruskal-Wallis and Mann-Whitney tests. The results of the average duration of tail bleeding time for each group is DM + Warfarin for 1200 ± 0.00 seconds, DM + Aquades for 913 ± 194.84 seconds, Normal group + Warfarin for 1173.3 ± 65.31 seconds, Normal + Aquades for 619.3 ± 319.64 seconds. The Kruskal-Wallis test showed that there was an effect of warfarin on tail bleeding time.

Latar Belakang: Radiografer Rumah Sakit berisiko terpapar dengan radiasi sinar-X yang dihasilkan oleh alat penunjang diagnostik dan terapi di Instalasi Radiologi. Paparan radiasi sinar-X yang diterima radiografer secara terus-menerus dapat meningkatkan risiko paparan radiasi kumulatif selama bekerja sehingga mempengaruhi kesehatan jangka panjang. Efek paparan radiasi pada tubuh bervariasi tergantung pada tingkat radiosensitivitas sel. Sel yang paling sensitif adalah sel limfosit. Tujuan: Mengetahui hubungan paparan sinar-X dengan jumlah limfosit pada radiografer di Rumah Sakit Umum Daerah Provinsi Nusa Tenggara Barat (RSUD Provinsi NTB). Metode: Penelitian ini menggunakan desain observasional analitik cross sectional. Populasi penelitian yaitu radiografer di Instalasi Radiologi RSUD Provinsi NTB tahun 2020 sebanyak 12 orang. Sampel ditentukan dengan teknik total sampling dan diperoleh 9 responden sesuai kriteria yang ditentukan. Paparan radiasi sinar-X didapat melalui hasil pemantauan dosis radiasi radiografer tahun 2018-2020 dan jumlah limfosit didapat melalui pemeriksaan laboratorium. Data yang terkumpul dianalisis menggunakan uji korelasi Pearson melalui SPSS 23.0. Hasil: Rerata dosis radiasi yang diterima radiografer tahun 2018-2020 sebesar 0,076 mSv, rerata jumlah limfosit sebesar 29,489%. Hasil uji korelasi Pearson menunjukkan paparan sinar-X tidak berhubungan dengan jumlah limfosit pada radiografer di RSUD Provinsi NTB dengan hubungan sangat lemah dan berpola negatif (p-value 0,704; r −0,148). Kesimpulan: Paparan sinar-X tidak berhubungan dengan jumlah limfosit pada radiografer di RSUD Provinsi NTB.Kata kunci: Paparan sinar-X, jumlah limfosit, radiografer. ABSTRACTBackground: Radiographers are at risk of being exposed to X-ray radiation produced by diagnostic and therapeutic support devices in radiology installations. Continuous exposure of X-ray radiation that received by radiographers can increase the risk of cumulative radiation exposure during work that can affect long-term health. The effects of radiation exposure on the body vary depending on the level of radiosensitivity of the cells. The most sensitive cells are lymphocytes. Objective: To analyze X-ray exposure with lymphocyte count in radiographers at the Regional Public Hospital of West Nusa Tenggara Province (RSUD Provinsi NTB). Methods: This research use observational cross sectional analytic study. Population in this research was 12 radiographers who worked in Radiology Installation of the Regional Public Hospital of West Nusa Tenggara Province. The sample was determined by total sampling and obtained 9 respondents according to the specified criteria. X-ray radiation exposure was obtained from the results of monitoring doses from 2018-2020 and the lympgocyte count obtained through laboratory tests. The collected data were analyzed using Pearson correlation test through Statistic Product and Service Solution version 23.0. Results: The results showed that the average radiation dose received by radiographers in 2018-2020 was 0.076 mSv and the average lymphocytes count was 29.489%. The results of the Pearson correlation test showed that there was no correlation between X-ray exposure and lymphocyte count in radiographers at RSUD Provinsi NTB with a very weak correlation and a negative pattern (p-value 0.704; r −0.148). Conclusion: There was no correlation between X-ray exposure and lymphocyte count in radiographers at RSUD Provinsi NTB.Key words: X-ray exposure, lymphocyte count, radiographer.

Pemanfaatan tanaman rimpang atau tanaman toga untuk menjaga kesehatan masyarakat Indonesia telah dilakukan sejak dulu, salah satunya yaitu tanaman Sirsak (Annona muricata Linn). Tanaman sirsak memiliki berbagai macam manfaat salah satunya digunakan untuk menstabilkan kadar glukosa darah. Tanaman sirsak memiliki beberapa senyawa yang terkandung didalamnya yaitu flavonoid, quercentin, dan tannin. Flavonoid bekerja menurunkan kadar glukosa darah dengan cara meregenerasi sel-sel β pankreas yang rusak, quercentin dengan cara menghambat enzim α-glukosidase sehingga tidak akan dipecah menjadi monosakarida, tannin dengan cara menghambat penyerapan glukosa pada usus halus. Untuk mengetahui efektifitas pemberian air rebusan daun sirsak terhadap kadar glukosa darah populasi sehat. Penelitian analitik eksperimen dengan desain penelitian pre-eksperimental. Teknik pengambilan sampel menggunakan teknik Purposive sampling. Penelitian dilakukan di BTN Griya Lingkar Mandiri pada 1 Februari 2020. Sampel penelitian merupakan sampel sehat sebanyak 40 responden. Data yang diperoleh dianalisis dengan uji korelasi McNemar. Batas nilai signifikasi adalah (p<0.05). Berdasarkan hasil penelitian, dari 40 sampel ditemukan sebanyak 36 sampel mengalami penurunan, dan 4 sampel mengalami peningkatan. Uji statistik menunjukkan pemberian air rebusan daun sirsak terhadap kadar glukosa darah memiliki efektifitas yang baik. Terdapat efektifitas yang bermakna dari pemberian air rebusan daun sirsak terhadap kadar glukosa darah populasi sehat.

This research aims to prove and analyze the influence of competence,work characteristics, work environment, spiritual quotient, onorganizational commitment, organizational citizenship behavior (OCB)and employee performance in the Laboratory Installation of RSUD PatutPatuh Patju West Lombok. This study is a causal explanatory study. Asample of 38 respondents, data analysis with Partial Least Square (PLS).The results showed there was a significant positive influence on:competence to OCB and employee performance; rusteristic work towardsorganizational commitment; work environment to organizationalcommitment; organizational commitment to OCB and employeeperformance; OCB on employee performance. Gained insignificantinfluence on: competence to organizational commitment; rusteristic ofemployment against OCB and employee performance; work environmenttowards OCB and employee performance; Spiritual quotient toorganizational commitment, OCB and employee performance. Theconclusion of the results of the study is that there are seven hypothesesthat can be accepted and there are eight hypotheses that are rejected.