Limited research exists in the literature regarding the biomechanics of the jump-landing sequence in individuals that experience symptoms of muscle damage. The present study investigated the effects of knee localized muscle damage on sagittal plane landing biomechanics during drop vertical jump (DVJ). Thirteen regional level athletes performed five sets of 15 maximal eccentric voluntary contractions of the knee extensors of both legs at 60°/s. Pelvic and lower body kinematics and kinetics were measured pre- and 48 h post-eccentric exercise. The examination of muscle damage indicators included isometric torque, muscle soreness, and serum creatine kinase (CK) activity. The results revealed that all indicators changed significantly following eccentric exercise (p < 0.05). Peak knee and hip joint flexion as well as peak anterior pelvic tilt significantly increased, whereas vertical ground reaction force (GRF), internal knee extension moment, and knee joint stiffness significantly decreased during landing (p < 0.05). Therefore, the participants displayed a softer landing pattern following knee-localized eccentric exercise while being in a muscle-damaged state. This observation provides new insights on how the DVJ landing kinematics and kinetics alter to compensate the impaired function of the knee extensors following exercise-induced muscle damage (EIMD) and residual muscle soreness 48 h post-exercise.

The present study pertains to a key aspect of human-robot collaborative systems which is usually underestimated, namely occupational health prolepsis. The aim of this investigation was to assess the biomechanical effects of manual symmetric load lifting related to a synergistic agricultural task that utilizes an unmanned ground vehicle to undertake the carriage of loads. Towards that goal, kinetic and kinematic data were collected from the lower extremities of thirteen experienced workers, by testing three different deposit heights (70, 80, 90 cm) corresponding to possible adjustments of the available agricultural robot. Moreover, the muscle activation levels of three lower extremity muscles and one trunk muscle were evaluated via a wireless electromyography system. Overall, the experimental findings revealed that the lower examined load height was associated with larger knee flexion moments and hip extension moments. Nevertheless, this height was related to lower activation mainly of the erectus spinae muscles. Finally, insignificant alterations were observed for the ankle joint as well as the activation levels of the other muscles. Consequently, a height equal to 90 cm is suggested, however, by avoiding extreme lumbar postures. The current results can be exploited for possible ergonomic interventions concerning the optimal deposit height of a robotic platform when a similar case is designed.

Ischemic stroke (IS) exhibits significant heterogeneity in terms of etiology and pathophysiology. Several recent studies highlight the significance of inflammation in the onset and progression of IS. White blood cell subtypes, such as neutrophils and monocytes, participate in the inflammatory response in various ways. On the other hand, high-density lipoproteins (HDL) exhibit substantial anti-inflammatory and antioxidant actions. Consequently, novel inflammatory blood biomarkers have emerged, such as neutrophil to HDL ratio (NHR) and monocyte to HDL ratio (MHR). Literature research of two databases (MEDLINE and Scopus) was conducted to identify all relevant studies published between 1 January 2012 and 30 November 2022 dealing with NHR and MHR as biomarkers for IS prognosis. Only full-text articles published in the English language were included. Thirteen articles have been traced and are included in the present review. Our findings highlight the utility of NHR and MHR as novel stroke prognostic biomarkers, the widespread application, and the calculation of which, along with their inexpensive cost, make their clinical application extremely promising.

The purpose of this paper is to present the design, construction, and technical aspects of a prototype upper extremities lever-driven exercise system, called FIT-WHEEL (Functional and Intelligent Training system for WHEELchair users), as well as the preliminary experimental measurements conducted to test the device’s usability in healthy individuals. FIT-WHEEL was developed to provide a training modality that combines the known benefits of eccentric exercise and lever-propelled wheelchairs. Eleven healthy male participants performed, seven days apart, a moderate intensity concentric and eccentric exercise protocol on FIT-WHEEL consisting of 30 trials of both upper extremities at 30% of peak concentric and peak eccentric force, respectively. At the end of each exercise bout, participants completed a number of valid and reliable instruments examining attitudes, intention and enjoyment during concentric or eccentric exercise on the FIT-WHEEL system as well as the usability of the two exercise protocols on the novel lever-driven exercise system. Statistical analyses revealed high scores in all the examined parameters (attitudes, intention, enjoyment, and usability) in both eccentric and concentric exercise protocols, without any significant differences emerging between them. Moreover, total mechanical work during eccentric exercise was 18.3% higher compared to concentric exercise performed on the FIT-WHEEL training system (p = 0.001). The preliminary experimental results discussed serve as an initial step to implement lever-driven eccentric exercise in wheelchair dependent populations in the future and evaluate the potential long-term benefits and limitations.