Background<br />The prevalence of diabetes in Indonesia continues to increase and causes many complications. Fruits of Phaleria macrocarpa (Scheff.) Boerl. (PM) are used in the traditional health system of the Indonesians, as effective remedy in the management of diabetes mellitus. The aim of this study was to evaluate the effect and magnitude of doses of PM dry fruit extract (PME) on blood glucose levels in healthy adults.<br /><br />Methods<br />This research was of pre-posttest design involving 30 healthy volunteer subjects aged 20-55 years receiving glucose loads. At pre-test the subjects were given orally 75 g glucose, and at post-test they were given PME at doses of 125 mg and 250 mg. Data collection included anthropometric examination and blood glucose level. The area under the curve (AUC) of blood glucose levels was measured at 0, 15, 30, 60, 120 and 180 minutes. Data analysis was performed using paired t-test with p &lt;0.05.<br /><br />Results<br />The percentage of reduction in AUC between pre- and post-test after administration of PME 125 mg was 12.1% and significant (p=0.000). But the percentage of reduction in AUC between pre- and post-test after administration of PME 250 mg was 4.07% and not significant (p=0.06). The reduction in AUC between post-test PME 125 mg vs PME 250 mg showed significant results (p=0.011).<br /><br />Conclusion <br />This study demonstrated that a dose of 125 mg Phaleria macrocarpa (Scheff.) Boerl. dry extract has a hypoglycemic effect in healthy adults, and may therefore be suitable for use as traditional anti-diabetic drug.

Pandemi Covid-19 telah membawa dampak pada berbagai kehidupan salah satunya kesehatan. Untuk menekan laju penularan dari Covid-19, pemerintah mengeluarkan aturan pembatasan pergerakan masyarakat. Masalah kesehatan lain pun timbul diantaranya berat badan yang meningkat,  pola makan yang tidak seimbang, dan aktifitas fisik yang rendah. Gaya hidup buruk memperparah penyakit metabolik yaitu diabetes melitus (DM). Berdasarkan Riskesda tahun 2018, prevalensi diabetes melitus di Jakarta meningkat menjadi 3,4%. Salah satu faktor resiko diabetes mellitus yaitu obesitas. Obesitas ditandai dengan peningkatan berat badan oleh karena ketidakseimbangan asupan energi dan penggunaan energi. Mitra pengabdian yaitu Vihara Pitakananda, yang bertempat di kelurahan Angke, Jakarta Barat. Sasaran pengabdian adalah warga sekitar vihara yang memiliki profesi sebagai buruh harian dan pedagang pasar. Pengabdian ini bertujuan meningkatkan pengetahuan pola hidup sehat dan status kesehatan masyarakat di masa pandemi. Metode yang digunakan berupa konsultasi, pengukuran Indeks Massa Tubuh (IMT) dan pengobatan. Pengabdian dilaksanakan pada 14 Maret 2021 pada Vihara Pitakananda di kelurahan Angke, Jakarta Barat. Peserta dan tim PKM mengikuti protokol kesehatan yang berlaku sebagai pencegahan Covid-19. Hasil pengabdian menunjukan terdapatnya peserta dengan IMT berat badan lebih sebesar 50,9% dan obesitas 21,1%. Penyakit tekanan darah tinggi ditemukan sejumlah 19,3%.  Peserta yang berkonsultasi diberikan edukasi, obat dan suplemen yang dapat meningkatkan status kesehatan. Antusiasme peserta yang tinggi mendorong kami melaksanakan kegiatan pengabdian secara berkala agar kebiasaan pola makan menjadi baik, aktivitas fisik yang optimal dapat tercipta dan status kesehatan dapat meningkat.

Background: Children's immunity system is relatively lower on first year of life, causing atopic babies, leading to allergy. Ideally, newborn babies are given breast milk as main food source on the first 6 months, but often being replaced with cow milk which can induce Cow's Milk Protein Allergy. For the alternative can replace it with soymilk formula which contains phytoestrogen from isoflavon, which works just like estrogen. The aim of this study to determine whether administration of soymilk formula is capable on increasing estrogen level and reducing testosterone level on male infant white Wistar rats (Rattus norvegicus). Materials and Methods: This research used post test only control group design. Samples were consisted of 36 infant male white Wistar rats aged 7 days, weighing from 10-15 grams, divided into 2 groups, control group which was given cow's milk and intervention group which was given soymilk. Each group were given intervention with the dose 5% of BW (grams), given twice-a-day orally for 21 days, and subsequently in the morning their blood samples were taken to examine the level of estrogen and testosterone hormone. Results: The study showed that the level of estrogen on intervention group was significantly higher than the control group with mean estrogen level of 0.55±0.03 pg/mL in the control group and 0.82±0.01 pg/mL in the intervention group, while the mean testosterone level was significantly lower on intervention group compared with control group (p<0.05) with 3.25±0.15 ng/mL on control group and 2.36±0.22 ng/mL on intervention group. Conclusion: Soymilk was able to increase estrogen level and reduce testosterone level on male infant white Wistar rats (Rattus norvegicus).

Background: Data in 2013 states that the prevalence of acute respiratory infections (ARI) is 25%. One of the factors that cause ISPA is air pollution. This factor is one of the risk factors for motorcycle taxi drivers who are always exposed to air pollution. Knowledge of ARI that is sufficient to influence the use of masks can help prevent ARI from occurring. Objective: This study aims to determine the relationship between knowledge of ARI and the behaviour of using masks among online motorcycle drivers. Methods: This study was an analytical observational with a cross-sectional design attended by 139 online motor cycle drivers around Grogol, Petamburan, West Jakarta, from July to December 2017. Data collection was done by filling out a questionnaire that includes demographic data, the use of masks, and knowledge of ARI. Data analysis used Fisher's test with significance level p<0,05. Results: A total of 139 respondents were collected, consisting of 131 (94.2%) men and 8 (5.8%) women. The average age of ≥ 30 years old is 77 (55.4%) people. Most respondents' education level was SMA/SMK/SLTA as many as 111 (79.9%) people. From the results of Fisher's test, it was found that the probability value p=0.362 was greater than the significance value (0.05). Conclusion: There is no significant relationship between the level of knowledge about ARI and the use of masks among online motorcycle drivers.